mynn myoneurin [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mynnprovided by ZNC
Official Full Name: myoneurinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5378
See related: Ensembl:ENSDARG00000007271 AllianceGenome:ZFIN:ZDB-GENE-030131-5378
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55724; wu:fd15c04
Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cartilage development and regulation of BMP signaling pathway. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in central nervous system; heart; pectoral fin; and pharyngeal arch. Orthologous to human MYNN (myoneurin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 24

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (26328782..26343902)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (26183743..26198916)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fd15c04.x1 (e-PCR)
- UniSTS:204192

fk91b01.x1 (e-PCR)
- UniSTS:201706

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cartilage development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cartilage development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of BMP signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of cytokine production	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: myoneurin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199768.1 → NP_956062.1 myoneurin

See identical proteins and their annotated locations for NP_956062.1

Status: PROVISIONAL

Source sequence(s)

BC045441

UniProtKB/Swiss-Prot

Q7ZVR6

Related

ENSDARP00000016471.7, ENSDART00000003884.9

Conserved Domains (5) summary

smart00225
Location:25 → 113

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00017
Location:559 → 579

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:557 → 579

zf-C2H2; Zinc finger, C2H2 type

pfam00651
Location:14 → 114

BTB; BTB/POZ domain

pfam13465
Location:571 → 596

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007135.7 Reference GRCz11 Primary Assembly

Range

26328782..26343902

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005162774.5 → XP_005162831.1 myoneurin isoform X1

UniProtKB/TrEMBL

A0A8M2B9Q5

Conserved Domains (5) summary

smart00225
Location:25 → 113

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00017
Location:557 → 577

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:555 → 577

zf-C2H2; Zinc finger, C2H2 type

pfam00651
Location:14 → 114

BTB; BTB/POZ domain

pfam13465
Location:569 → 594

zf-H2C2_2; Zinc-finger double domain