ahsa1b AHA1, activator of heat shock protein ATPase homolog 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ahsa1bprovided by ZNC
Official Full Name: AHA1, activator of heat shock protein ATPase homolog 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-664
See related: Ensembl:ENSDARG00000100317 AllianceGenome:ZFIN:ZDB-GENE-030131-664
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ahsa1l; id:ibd5076; wu:fb38h08
Summary: Predicted to enable ATPase activator activity. Predicted to be involved in protein folding. Predicted to be active in cytosol. Is expressed in several structures, including digestive system; gonad; head; heart; and otic vesicle. Orthologous to human AHSA1 (activator of HSP90 ATPase activity 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (43850516..43863700, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (43736751..43749935, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gene expression and functional analysis of Aha1a and Aha1b in stress response in zebrafish.
Title: Gene expression and functional analysis of Aha1a and Aha1b in stress response in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATPase activator activity	IEA Inferred from Electronic Annotation more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: activator of 90 kDa heat shock protein ATPase homolog 1b

Names: AHA1, activator of heat shock 90kDa protein ATPase homolog 1, like; AHA1, activator of heat shock protein ATPase homolog 1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212602.1 → NP_997767.1 activator of 90 kDa heat shock protein ATPase homolog 1b

See identical proteins and their annotated locations for NP_997767.1

Status: PROVISIONAL

Source sequence(s)

BC055523

UniProtKB/TrEMBL

Q7SXN3

Related

ENSDARP00000131241.1, ENSDART00000157530.2

Conserved Domains (3) summary

cd08892
Location:208 → 333

SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins

smart01000
Location:29 → 158

Aha1_N; Activator of Hsp90 ATPase, N-terminal

COG5580
Location:19 → 337

COG5580; Activator of HSP90 ATPase [Posttranslational modification, protein turnover, chaperones]