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    c8g complement component 8, gamma polypeptide [ Danio rerio (zebrafish) ]

    Gene ID: 393837, updated on 9-Dec-2024

    Summary

    Official Symbol
    c8gprovided by ZNC
    Official Full Name
    complement component 8, gamma polypeptideprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1898
    See related
    Ensembl:ENSDARG00000032098 AllianceGenome:ZFIN:ZDB-GENE-040426-1898
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77874
    Summary
    Predicted to act upstream of or within complement activation. Predicted to be located in extracellular region. Predicted to be part of membrane attack complex. Is expressed in liver. Orthologous to human C8G (complement C8 gamma chain). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See c8g in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (17031129..17039617, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (16886710..16895198, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene prostaglandin D2 synthase b, tandem duplicate 2 Neighboring gene prostaglandin D2 synthase b, tandem duplicate 1 Neighboring gene methionine sulfoxide reductase B2 Neighboring gene armadillo repeat containing 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    complement component C8 gamma chain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200863.1NP_957157.1  complement component C8 gamma chain precursor

      See identical proteins and their annotated locations for NP_957157.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062865
      UniProtKB/TrEMBL
      A0A8M1PFX2, Q6P5J2
      Related
      ENSDARP00000048822.6, ENSDART00000048823.8
      Conserved Domains (1) summary
      pfam00061
      Location:59194
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      17031129..17039617 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)