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    polm polymerase (DNA directed), mu [ Danio rerio (zebrafish) ]

    Gene ID: 393218, updated on 9-Dec-2024

    Summary

    Official Symbol
    polmprovided by ZNC
    Official Full Name
    polymerase (DNA directed), muprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-911
    See related
    Ensembl:ENSDARG00000103470 AllianceGenome:ZFIN:ZDB-GENE-040426-911
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    polmu; zgc:56122
    Summary
    Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within DNA repair. Predicted to be active in nucleus. Is expressed in pleuroperitoneal region and thymus. Orthologous to human POLM (DNA polymerase mu). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See polm in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (45015225..45029016, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (45168613..45182599, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene H2A.Z variant histone 2b Neighboring gene ventrally expressed dharma/bozozok antagonist Neighboring gene glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b Neighboring gene mitochondrial ribosomal protein S24

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC56122

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding  
    enables DNA polymerase activity  
    enables DNA-directed DNA polymerase activity  
    enables DNA-directed DNA polymerase activity  
    enables metal ion binding  
    enables nucleotidyltransferase activity  
    enables transferase activity  
    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    DNA-directed DNA/RNA polymerase mu
    Names
    DNA polymerase mu
    NP_956542.1
    XP_068079836.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200248.1NP_956542.1  DNA-directed DNA/RNA polymerase mu

      See identical proteins and their annotated locations for NP_956542.1

      Status: PROVISIONAL

      Source sequence(s)
      BC047832
      UniProtKB/TrEMBL
      Q7ZUU0
      Related
      ENSDARP00000141586.1, ENSDART00000167878.2
      Conserved Domains (2) summary
      cd00141
      Location:160505
      NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
      smart00483
      Location:158506
      POLXc; DNA polymerase X family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      45015225..45029016 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223735.1XP_068079836.1  DNA-directed DNA/RNA polymerase mu isoform X1

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