zgc:123258 zgc:123258 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:123258provided by ZNC
Official Full Name: zgc:123258provided by ZNC
Primary source: ZFIN:ZDB-GENE-051120-84
See related: AllianceGenome:ZFIN:ZDB-GENE-051120-84
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in membrane protein proteolysis. Predicted to be located in organelle membrane. Predicted to be active in bounding membrane of organelle and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jan 2025]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: Un

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_008805481.1 (6712..7104, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_008805481.1 (6712..7104, complement)

NW_008805481.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables aspartic endopeptidase activity, intramembrane cleaving	IBA Inferred from Biological aspect of Ancestor more info
enables aspartic endopeptidase activity, intramembrane cleaving	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in membrane protein proteolysis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in Golgi-associated vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasmic side of endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in lumenal side of endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in organelle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC641502

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001037439.1 → NP_001032516.1 uncharacterized protein LOC641502 precursor

See identical proteins and their annotated locations for NP_001032516.1

Status: PREDICTED

Source sequence(s)

BC109426

UniProtKB/TrEMBL

Q32LU5

Conserved Domains (2) summary

cd02129
Location:36 → 155

PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...

cl01342
Location:206 → 510

Peptidase_A22B; Signal peptide peptidase