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    foxj3 forkhead box J3 [ Danio rerio (zebrafish) ]

    Gene ID: 797147, updated on 9-Dec-2024

    Summary

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    Official Symbol
    foxj3provided by ZNC
    Official Full Name
    forkhead box J3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-101005-1
    See related
    Ensembl:ENSDARG00000075774 AllianceGenome:ZFIN:ZDB-GENE-101005-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fd99b01
    Summary
    Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human FOXJ3 (forkhead box J3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See foxj3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (26231899..26362294, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (25994454..26124678, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene kazrin, periplakin interacting protein b Neighboring gene uncharacterized LOC137496699 Neighboring gene PR domain containing 2, with ZNF domain b Neighboring gene phosphopantothenoylcysteine synthetase Neighboring gene UTP3 small subunit processome component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionarily ancient association of the FoxJ1 transcription factor with the motile ciliogenic program. Vij S, et al. PLoS Genet, 2012. PMID 23144623, Free PMC Article
    2. Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Tonelli F, et al. Matrix Biol, 2020 Aug. PMID 32173581
    3. A new member of the forkhead box protein family in zebrafish: Domain composition, phylogenetic implication and embryonic expression pattern. Zeng CW, et al. Gene Expr Patterns, 2020 Jan. PMID 31917260
    4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    forkhead box protein J3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001326388.1 → NP_001313317.1  forkhead box protein J3

      Status: VALIDATED

      Source sequence(s)
      BX005135, CR318604
      UniProtKB/TrEMBL
      A0A2R8Q307, A0A8M1P393
      Related
      ENSDARP00000145163.1, ENSDART00000184654.1
      Conserved Domains (2) summary
      pfam00250
      Location:62 → 139
      Forkhead; Forkhead domain
      pfam04592
      Location:327 → 394
      SelP_N; Selenoprotein P, N terminal region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      26231899..26362294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001922238.7 → XP_001922273.1  forkhead box protein J3 isoform X1

      UniProtKB/TrEMBL
      A0A8M1QHP6, E7F138
      Related
      ENSDARP00000102208.3, ENSDART00000115037.4
      Conserved Domains (2) summary
      pfam00250
      Location:62 → 139
      Forkhead; Forkhead domain
      pfam04592
      Location:327 → 394
      SelP_N; Selenoprotein P, N terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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