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    phldb2b pleckstrin homology-like domain, family B, member 2b [ Danio rerio (zebrafish) ]

    Gene ID: 560668, updated on 9-Dec-2024

    Summary

    Official Symbol
    phldb2bprovided by ZNC
    Official Full Name
    pleckstrin homology-like domain, family B, member 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3235
    See related
    Ensembl:ENSDARG00000074843 AllianceGenome:ZFIN:ZDB-GENE-030131-3235
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc31d06; wu:fc31d06; si:dkey-11p10.8
    Summary
    Predicted to be involved in regulation of microtubule cytoskeleton organization. Predicted to be active in basal cortex. Orthologous to human PHLDB2 (pleckstrin homology like domain family B member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See phldb2b in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (25093297..25166652, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (24948123..25021544, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene myotubularin related protein 6 Neighboring gene APC membrane recruitment protein 2 Neighboring gene uncharacterized LOC108181555 Neighboring gene si:ch73-264p11.1 Neighboring gene phosphatidylinositol-specific phospholipase C, X domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    pleckstrin homology-like domain family B member 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      25093297..25166652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217225.1 → XP_068073326.1  pleckstrin homology-like domain family B member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9P651
      Related
      ENSDARP00000116815.2, ENSDART00000141601.4
    2. XM_021470325.2 → XP_021326000.1  pleckstrin homology-like domain family B member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PUG2, A0A8M9PXY1
      Conserved Domains (5) summary
      cd00060
      Location:51 → 149
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd14673
      Location:1360 → 1464
      PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
      cl25732
      Location:680 → 915
      SMC_N; RecF/RecN/SMC N terminal domain
      cl27427
      Location:986 → 1029
      AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
      cl28033
      Location:189 → 500
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
    3. XM_068217227.1 → XP_068073328.1  pleckstrin homology-like domain family B member 2 isoform X4

      UniProtKB/TrEMBL
      A0A8M9P651
    4. XM_068217226.1 → XP_068073327.1  pleckstrin homology-like domain family B member 2 isoform X3

      UniProtKB/TrEMBL
      A0A8M9P651
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