eif1axb eukaryotic translation initiation factor 1A X-linked b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eif1axbprovided by ZNC
Official Full Name: eukaryotic translation initiation factor 1A X-linked bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1319
See related: Ensembl:ENSDARG00000057912 AllianceGenome:ZFIN:ZDB-GENE-030131-1319
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb26b09; wu:fb38c07; wu:fb66g07; wu:fk26d12; zgc:110087
Summary: Predicted to enable translation initiation factor activity. Acts upstream of or within erythrocyte maturation; regulation of hemoglobin biosynthetic process; and regulation of miRNA processing. Predicted to be active in cytoplasm. Orthologous to human EIF1AX (eukaryotic translation initiation factor 1A X-linked). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 24

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (24164227..24168473, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (24019053..24023299, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

eIF1A is a novel component of the Ago2-centred RNA-induced silencing complexes (RISCs) and augments Ago2-dependent RNAi and miRNA biogenesis.
Title: eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.

Submit: New GeneRIF Correction

General gene information

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Markers

fb26b09 (e-PCR)
- UniSTS:187152

fk26d12.x1 (e-PCR)
- UniSTS:200722

fc02e06.x1 (e-PCR)
- UniSTS:192071

fj26d08.y1 (e-PCR)
- UniSTS:198911

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within erythrocyte maturation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of hemoglobin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of miRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 1A X-linked b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.