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    ccl19a.1 chemokine (C-C motif) ligand 19a, tandem duplicate 1 [ Danio rerio (zebrafish) ]

    Gene ID: 794891, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ccl19a.1provided by ZNC
    Official Full Name
    chemokine (C-C motif) ligand 19a, tandem duplicate 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060526-181
    See related
    Ensembl:ENSDARG00000058389 AllianceGenome:ZFIN:ZDB-GENE-060526-181
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ccl-c5a; si:ch211-89f7.4
    Summary
    Predicted to enable chemokine activity. Acts upstream of or within dorsal/ventral pattern formation. Predicted to be located in extracellular space. Orthologous to human CCL19 (C-C motif chemokine ligand 19). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See ccl19a.1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (13353858..13392579)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (12853643..12892362)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene YdjC chitooligosaccharide deacetylase homolog Neighboring gene ubiquitin-conjugating enzyme E2L 3b Neighboring gene chemokine (C-C motif) ligand 19a, tandem duplicate 2 Neighboring gene tectonic family member 2 Neighboring gene SEC14-like lipid binding 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Olfactory sensory neurons mediate ultrarapid antiviral immune responses in a TrkA-dependent manner. Sepahi A, et al. Proc Natl Acad Sci U S A, 2019 Jun 18. PMID 31160464, Free PMC Article
    2. A novel CC chemokine ligand 2 like gene from ayu Plecoglossus altivelis is involved in the innate immune response against to Vibrio anguillarum. Yu L, et al. Fish Shellfish Immunol, 2019 Apr. PMID 30797066
    3. Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder. Laghi V, et al. Front Cell Infect Microbiol, 2022. PMID 35360100, Free PMC Article
    4. Transcriptome profiling of zebrafish infected with Streptococcus suis. Wu Z, et al. Microb Pathog, 2010 May. PMID 20206250
    5. Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection. Stockhammer OW, et al. J Immunol, 2009 May 1. PMID 19380811

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within dorsal/ventral pattern formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within dorsal/ventral pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within immune response IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-C motif chemokine 19a.1
    Names
    CCL-chr5a
    CCL19aa
    chemokine CCL-C5a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082906.2 → NP_001076375.2  C-C motif chemokine 19a.1 precursor

      See identical proteins and their annotated locations for NP_001076375.2

      Status: PROVISIONAL

      Source sequence(s)
      AB331770
      UniProtKB/TrEMBL
      A9ZPF5
      Related
      ENSDARP00000156538.1, ENSDART00000191190.1
      Conserved Domains (1) summary
      pfam00048
      Location:34 → 91
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      13353858..13392579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165054.2 → XP_005165111.1  C-C motif chemokine 19a.1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BCA0, A2BIR2
      Related
      ENSDARP00000090385.3, ENSDART00000099611.4
      Conserved Domains (1) summary
      pfam00048
      Location:34 → 91
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like
    Nucleotide Protein
    Heading Accession and Version

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