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    spag1b sperm associated antigen 1b [ Danio rerio (zebrafish) ]

    Gene ID: 768178, updated on 4-Jan-2025

    Summary

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    Official Symbol
    spag1bprovided by ZNC
    Official Full Name
    sperm associated antigen 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-512
    See related
    Ensembl:ENSDARG00000069499 AllianceGenome:ZFIN:ZDB-GENE-061013-512
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153288
    Summary
    Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in female organism. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 28. Orthologous to human SPAG1 (sperm associated antigen 1). [provided by Alliance of Genome Resources, Jan 2025]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See spag1b in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (54632865..54640400, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (54827391..54831410, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488006 Neighboring gene serine/threonine-protein kinase pim-2 Neighboring gene F-box protein 43 Neighboring gene regulator of G protein signaling 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Shared acquired genomic changes in zebrafish and human T-ALL. Rudner LA, et al. Oncogene, 2011 Oct 13. PMID 21552289, Free PMC Article
    2. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Choksi SP, et al. Development, 2014 Sep. PMID 25139857, Free PMC Article
    3. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Newman M, et al. Mol Brain, 2019 May 3. PMID 31053140, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC768178

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077321.1 → NP_001070789.1  uncharacterized protein LOC768178

      See identical proteins and their annotated locations for NP_001070789.1

      Status: PREDICTED

      Source sequence(s)
      BC124658
      UniProtKB/TrEMBL
      Q08BM1
      Related
      ENSDARP00000091981.5, ENSDART00000101207.5
      Conserved Domains (4) summary
      sd00006
      Location:198 → 222
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:486 → 517
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:194 → 258
      TPR_11; TPR repeat
      pfam13432
      Location:233 → 294
      TPR_16; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      54632865..54640400 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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