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    ero1b endoplasmic reticulum oxidoreductase 1 beta [ Danio rerio (zebrafish) ]

    Gene ID: 767700, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ero1bprovided by ZNC
    Official Full Name
    endoplasmic reticulum oxidoreductase 1 betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-744
    See related
    Ensembl:ENSDARG00000103915 AllianceGenome:ZFIN:ZDB-GENE-060929-744
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ero1lb; zgc:153032
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein folding in endoplasmic reticulum. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ERO1B (endoplasmic reticulum oxidoreductase 1 beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ero1b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (44502402..44522586)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (44240457..44260450)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene mitofusin 1b Neighboring gene si:ch1073-365p7.2 Neighboring gene G protein-coupled receptor 137Bb Neighboring gene nidogen 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. High-content screen using zebrafish (Danio rerio) embryos identifies a novel kinase activator and inhibitor. Geldenhuys WJ, et al. Bioorg Med Chem Lett, 2017 May 1. PMID 28320616, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC153032

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-disulfide reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiol oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein folding in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ERO1-like protein beta
    Names
    ERO1-like beta
    endoplasmic reticulum oxidoreductase beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076638.1 → NP_001070106.1  ERO1-like protein beta precursor

      See identical proteins and their annotated locations for NP_001070106.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124220
      UniProtKB/TrEMBL
      Q08CJ0
      Related
      ENSDARP00000139494.1, ENSDART00000169295.3
      Conserved Domains (1) summary
      pfam04137
      Location:48 → 446
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      44502402..44522586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005172944.5 → XP_005173001.1  ERO1-like protein beta isoform X1

      UniProtKB/TrEMBL
      A0A8M2BK75
      Conserved Domains (1) summary
      pfam04137
      Location:77 → 475
      ERO1; Endoplasmic Reticulum Oxidoreductin 1 (ERO1)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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