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    si:dkey-260j18.2 si:dkey-260j18.2 [ Danio rerio (zebrafish) ]

    Gene ID: 325231, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:dkey-260j18.2provided by ZNC
    Official Full Name
    si:dkey-260j18.2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3956
    See related
    Ensembl:ENSDARG00000101942 AllianceGenome:ZFIN:ZDB-GENE-030131-3956
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc60g01; wu:fc60g01
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See si:dkey-260j18.2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (14632757..14642187, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (14696800..14706230, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene F-box protein 46 Neighboring gene solute carrier family 5 member 2 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene prolyl 4-hydroxylase, alpha polypeptide III

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC325231

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079948.2 → NP_001073417.2  uncharacterized protein LOC325231

      See identical proteins and their annotated locations for NP_001073417.2

      Status: PREDICTED

      Source sequence(s)
      BC152491
      UniProtKB/TrEMBL
      A7MD61
      Related
      ENSDARP00000130659.1, ENSDART00000164166.2
      Conserved Domains (6) summary
      smart00612
      Location:394 → 436
      Kelch; Kelch domain
      smart00225
      Location:65 → 161
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:166 → 262
      BACK; BTB And C-terminal Kelch
      sd00038
      Location:337 → 377
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:54 → 157
      BTB; BTB/POZ domain
      pfam01344
      Location:335 → 371
      Kelch_1; Kelch motif

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      14632757..14642187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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