U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    nop53 NOP53 ribosome biogenesis factor [ Danio rerio (zebrafish) ]

    Gene ID: 322404, updated on 9-Dec-2024

    Summary

    Official Symbol
    nop53provided by ZNC
    Official Full Name
    NOP53 ribosome biogenesis factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051120-21
    See related
    Ensembl:ENSDARG00000100452 AllianceGenome:ZFIN:ZDB-GENE-051120-21
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb60b03; gltscr2; wu:fb60b03; zgc:123178
    Summary
    Predicted to enable 5S rRNA binding activity. Predicted to be involved in rRNA processing and ribosomal large subunit assembly. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See nop53 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (6652431..6666232)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (6655108..6669139)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene beta-secretase 2 Neighboring gene ATM serine/threonine kinase Neighboring gene gap junction delta-2 protein Neighboring gene distal membrane arm assembly component 2

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 5S rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal large subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosome biogenesis protein NOP53
    Names
    glioma tumor suppressor candidate region gene 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079946.2NP_001073415.2  ribosome biogenesis protein NOP53

      Status: VALIDATED

      Source sequence(s)
      CABZ01056393, CABZ01056394, CABZ01056395, CU633984
      UniProtKB/TrEMBL
      Q32LR6
      Related
      ENSDARP00000131696.2, ENSDART00000157678.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      6652431..6666232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)