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    C1orf210 chromosome 1 open reading frame 210 [ Homo sapiens (human) ]

    Gene ID: 149466, updated on 10-Dec-2024

    Summary

    Official Symbol
    C1orf210provided by HGNC
    Official Full Name
    chromosome 1 open reading frame 210provided by HGNC
    Primary source
    HGNC:HGNC:28755
    See related
    Ensembl:ENSG00000253313 MIM:620582; AllianceGenome:HGNC:28755
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TEMP
    Summary
    Predicted to be located in early endosome; plasma membrane; and recycling endosome. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in duodenum (RPKM 14.2), small intestine (RPKM 12.7) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See C1orf210 in Genome Data Viewer
    Location:
    1p34.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (43281877..43285857, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (43152383..43156345, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (43747548..43751252, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378685 Neighboring gene cilia and flagella associated protein 57 Neighboring gene uncharacterized LOC124904164 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:43735285-43735788 Neighboring gene transmembrane protein 125 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43751233-43751791 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:43751792-43752349 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 915 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:43786614-43787813 Neighboring gene tyrosine kinase with immunoglobulin like and EGF like domains 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:43813871-43814842 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:43814843-43815813 Neighboring gene MPL proto-oncogene, thrombopoietin receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Interactions

    General gene information

    Clone Names

    • MGC52423

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in early endosome  
    located_in plasma membrane  
    located_in recycling endosome  

    General protein information

    Preferred Names
    type III endosome membrane protein TEMP

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164829.2NP_001158301.1  type III endosome membrane protein TEMP

      See identical proteins and their annotated locations for NP_001158301.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC093420, AL696898, BC041633
      Consensus CDS
      CCDS481.1
      UniProtKB/Swiss-Prot
      D3DPX2, Q8IVY1
      Related
      ENSP00000429399.1, ENST00000423420.1
      Conserved Domains (1) summary
      pfam15176
      Location:2197
      LRR19-TM; Leucine-rich repeat family 19 TM domain
    2. NM_182517.3NP_872323.1  type III endosome membrane protein TEMP

      See identical proteins and their annotated locations for NP_872323.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC093420, BC041633, BM273035, BM784450
      Consensus CDS
      CCDS481.1
      UniProtKB/Swiss-Prot
      D3DPX2, Q8IVY1
      Related
      ENSP00000430918.1, ENST00000523677.6
      Conserved Domains (1) summary
      pfam15176
      Location:2197
      LRR19-TM; Leucine-rich repeat family 19 TM domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      43281877..43285857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011540802.3XP_011539104.1  type III endosome membrane protein TEMP isoform X1

      See identical proteins and their annotated locations for XP_011539104.1

      UniProtKB/Swiss-Prot
      D3DPX2, Q8IVY1
      Conserved Domains (1) summary
      pfam15176
      Location:2197
      LRR19-TM; Leucine-rich repeat family 19 TM domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      43152383..43156345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054334659.1XP_054190634.1  type III endosome membrane protein TEMP isoform X1

      UniProtKB/Swiss-Prot
      D3DPX2, Q8IVY1
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