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    zipt-2.4 Zinc transporter ZIP3 [ Caenorhabditis elegans ]

    Gene ID: 172230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zipt-2.4
    Official Full Name
    Zinc transporter ZIP3
    Primary source
    WormBase:WBGene00018897
    Locus tag
    CELE_F55F8.9
    See related
    AllianceGenome:WB:WBGene00018897
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zipt-2.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (5669945..5673352, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SSD domain-containing protein Neighboring gene Secreted protein Neighboring gene Uncharacterized protein Neighboring gene Mitochondrial import inner membrane translocase subunit TIM14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Zinc transporters ZIPT-2.4 and ZIPT-15 are required for normal C. elegans fecundity. Sue AC, et al. J Assist Reprod Genet, 2022 Jun. PMID 35501415, Free PMC Article
    2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in metal ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Zinc transporter ZIP3
    NP_001249971.1
    • Confirmed by transcript evidence
    NP_001367898.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5669945..5673352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001380347.2 → NP_001367898.1  Zinc transporter ZIP3 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91348
      Conserved Domains (1) summary
      pfam02535
      Location:4 → 438
      Zip; ZIP Zinc transporter

    2. NM_001263042.2 → NP_001249971.1  Zinc transporter ZIP3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001249971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4SKK4
      Conserved Domains (1) summary
      pfam02535
      Location:4 → 402
      Zip; ZIP Zinc transporter
    Nucleotide Protein
    Heading Accession and Version

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