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    Or2y8 olfactory receptor family 2 subfamily Y member 8 [ Mus musculus (house mouse) ]

    Gene ID: 211472, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or2y8provided by MGI
    Official Full Name
    olfactory receptor family 2 subfamily Y member 8provided by MGI
    Primary source
    MGI:MGI:3031207
    See related
    Ensembl:ENSMUSG00000062204 AllianceGenome:MGI:3031207
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr1373; GA_x6K02T2QP88-3283154-3284089
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or2y8 in Genome Data Viewer
    Location:
    11 B1.3; 11 31.86 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (52035420..52036355, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (52144593..52149130, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Neighboring gene predicted gene, 30631 Neighboring gene microRNA 3061 Neighboring gene olfactory receptor family 2 subfamily Y member 7 Neighboring gene predicted gene, 53705

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
    2. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    3. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123567, MGC140881

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor family 2 subfamily Y member 8
    Names
    MOR256-69_p
    olfactory receptor 1373
    olfactory receptor GA_x6K02T2QP88-3283154-3284089

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207227.1 → NP_997110.1  olfactory receptor family 2 subfamily Y member 8

      See identical proteins and their annotated locations for NP_997110.1

      Status: PROVISIONAL

      Source sequence(s)
      AY318584
      Consensus CDS
      CCDS24667.1
      UniProtKB/TrEMBL
      Q3B853, Q3B887, Q7TQT6
      Related
      ENSMUSP00000077384.2, ENSMUST00000078264.2
      Conserved Domains (2) summary
      pfam00001
      Location:41 → 289
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:32 → 304
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      52035420..52036355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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