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    H3c3 H3 clustered histone 3 [ Mus musculus (house mouse) ]

    Gene ID: 319148, updated on 9-Dec-2024

    Summary

    Official Symbol
    H3c3provided by MGI
    Official Full Name
    H3 clustered histone 3provided by MGI
    Primary source
    MGI:MGI:2448320
    See related
    Ensembl:ENSMUSG00000069310 AllianceGenome:MGI:2448320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H3c2; H3c4; H3c6; H3c7; H3c13; H3c14; H3c15; H3-143; Hist1h3c
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H3c3 in Genome Data Viewer
    Location:
    13 A3.1; 13 9.9 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23929025..23929504, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23745042..23745521, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene Hist1h1cR1 erythroid cis-regulatory module Neighboring gene family with sequence similarity 113, member A pseudogene Neighboring gene STARR-seq mESC enhancer starr_33971 Neighboring gene H1.2 linker histone, cluster member Neighboring gene STARR-seq mESC enhancer starr_33972 Neighboring gene STARR-positive B cell enhancer ABC_E1162 Neighboring gene STARR-positive B cell enhancer ABC_E210 Neighboring gene H2A clustered histone 5, pseudogene Neighboring gene H2B clustered histone 3

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H3.2
    Names
    H3-clustered histone 13
    H3-clustered histone 14
    H3-clustered histone 15
    H3-clustered histone 2
    H3-clustered histone 4
    H3-clustered histone 6
    H3-clustered histone 7
    histone cluster 1, H3c
    histone1, H3c

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175653.2NP_783584.1  histone H3.2

      See identical proteins and their annotated locations for NP_783584.1

      Status: REVIEWED

      Source sequence(s)
      AL590388
      Consensus CDS
      CCDS26362.1
      UniProtKB/Swiss-Prot
      A3KMN6, P84228, Q60582, Q78E59, Q8CGN9
      UniProtKB/TrEMBL
      A1L0V4, B9EI85
      Related
      ENSMUSP00000089346.3, ENSMUST00000091752.5
      Conserved Domains (1) summary
      PTZ00018
      Location:1136
      PTZ00018; histone H3; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      23929025..23929504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)