U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    P2ry14 purinergic receptor P2Y, G-protein coupled, 14 [ Mus musculus (house mouse) ]

    Gene ID: 140795, updated on 9-Dec-2024

    Summary

    Official Symbol
    P2ry14provided by MGI
    Official Full Name
    purinergic receptor P2Y, G-protein coupled, 14provided by MGI
    Primary source
    MGI:MGI:2155705
    See related
    Ensembl:ENSMUSG00000036381 AllianceGenome:MGI:2155705
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P2Y14; Gpr105; A330108O13Rik
    Summary
    Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Orthologous to human P2RY14 (purinergic receptor P2Y14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in subcutaneous fat pad adult (RPKM 13.2), large intestine adult (RPKM 3.9) and 20 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See P2ry14 in Genome Data Viewer
    Location:
    3 D; 3 28.96 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (59022044..59060913, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (59114623..59153492, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L13, pseudogene 6 Neighboring gene mediator complex subunit 12-like Neighboring gene STARR-positive B cell enhancer ABC_E6054 Neighboring gene STARR-seq mESC enhancer starr_07762 Neighboring gene STARR-seq mESC enhancer starr_07763 Neighboring gene G protein-coupled receptor 171 Neighboring gene RIKEN cDNA F630111L10 gene Neighboring gene STARR-seq mESC enhancer starr_07764 Neighboring gene STARR-seq mESC enhancer starr_07765 Neighboring gene predicted gene, 51434 Neighboring gene G protein-coupled receptor 87 Neighboring gene purinergic receptor P2Y, G-protein coupled 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General protein information

    Preferred Names
    P2Y purinoceptor 14
    Names
    G-protein coupled receptor 105
    UDP-glucose receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008497.2NP_001008497.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001008497.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AC115919, AK164982, BC058558
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Related
      ENSMUSP00000066669.7, ENSMUST00000065220.13
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. NM_001287119.1NP_001274048.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001274048.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AC115919
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Related
      ENSMUSP00000142601.2, ENSMUST00000196081.5
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    3. NM_001287120.1NP_001274049.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001274049.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AK164982, BY177387
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    4. NM_001287121.1NP_001274050.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001274050.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AK039791, AK164982, CF169635
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    5. NM_001287122.1NP_001274051.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001274051.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AK164982, CK622172
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    6. NM_001287123.1NP_001274052.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_001274052.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1 through 7 encode the same protein (isoform a).
      Source sequence(s)
      AK039791, AK164982
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Related
      ENSMUSP00000143070.2, ENSMUST00000197220.2
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    7. NM_001287124.1NP_001274053.1  P2Y purinoceptor 14 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) uses an alternate splice site in the 3' terminal exon which results in a distinct 5' UTR and causes translation initiation at an upstream start codon compared to variant 1. It encodes isoform b which is longer and has a distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC115919
      Consensus CDS
      CCDS79913.1
      UniProtKB/TrEMBL
      A0A0G2JEW9
      Related
      ENSMUSP00000142934.2, ENSMUST00000197841.2
      Conserved Domains (1) summary
      pfam00001
      Location:49304
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    8. NM_133200.4NP_573463.1  P2Y purinoceptor 14 isoform a

      See identical proteins and their annotated locations for NP_573463.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the shorter isoform (a). Variants 1 through 7 encode the same protein.
      Source sequence(s)
      AC115919, AK164982
      Consensus CDS
      CCDS17371.1
      UniProtKB/Swiss-Prot
      Q9ESG6
      UniProtKB/TrEMBL
      Q544F4
      Related
      ENSMUSP00000088642.5, ENSMUST00000091112.6
      Conserved Domains (1) summary
      pfam00001
      Location:40295
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      59022044..59060913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)