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    Gpr171 G protein-coupled receptor 171 [ Mus musculus (house mouse) ]

    Gene ID: 229323, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gpr171provided by MGI
    Official Full Name
    G protein-coupled receptor 171provided by MGI
    Primary source
    MGI:MGI:2442043
    See related
    Ensembl:ENSMUSG00000050075 AllianceGenome:MGI:2442043
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H963; A630006E05; F730001G15Rik
    Summary
    Enables neuropeptide binding activity and neuropeptide receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; regulation of feeding behavior; and regulation of sensory perception of pain. Acts upstream of or within negative regulation of myeloid cell differentiation. Located in plasma membrane. Orthologous to human GPR171 (G protein-coupled receptor 171). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in thymus adult (RPKM 4.5), spleen adult (RPKM 2.7) and 6 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Gpr171 in Genome Data Viewer
    Location:
    3 D; 3 28.94 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (59003869..59009242, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (59096448..59101821, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L13, pseudogene 6 Neighboring gene predicted gene, 25572 Neighboring gene mediator complex subunit 12-like Neighboring gene STARR-positive B cell enhancer ABC_E6054 Neighboring gene STARR-seq mESC enhancer starr_07762 Neighboring gene STARR-seq mESC enhancer starr_07763 Neighboring gene RIKEN cDNA F630111L10 gene Neighboring gene purinergic receptor P2Y, G-protein coupled, 14 Neighboring gene STARR-seq mESC enhancer starr_07764 Neighboring gene STARR-seq mESC enhancer starr_07765 Neighboring gene predicted gene, 51434 Neighboring gene G protein-coupled receptor 87

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (6) 
    • Targeted (2) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled peptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables G protein-coupled purinergic nucleotide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables neuropeptide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables neuropeptide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptor 171
    Names
    probable G-protein coupled receptor 171

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173398.3NP_775574.1  G-protein coupled receptor 171

      See identical proteins and their annotated locations for NP_775574.1

      Status: VALIDATED

      Source sequence(s)
      AC115919
      Consensus CDS
      CCDS17370.1
      UniProtKB/Swiss-Prot
      Q8BG55, Q8BTN1, Q8BY85, Q8CIF3
      Related
      ENSMUSP00000082115.5, ENSMUST00000085040.5
      Conserved Domains (1) summary
      pfam00001
      Location:37285
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      59003869..59009242 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)