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    Or10d4b olfactory receptor family 10 subfamily D member 4B [ Mus musculus (house mouse) ]

    Gene ID: 258276, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or10d4bprovided by MGI
    Official Full Name
    olfactory receptor family 10 subfamily D member 4Bprovided by MGI
    Primary source
    MGI:MGI:3030794
    See related
    Ensembl:ENSMUSG00000059867 AllianceGenome:MGI:3030794
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr960; MOR224-12
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or10d4b in Genome Data Viewer
    Location:
    9 A5.1; 9 20.98 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (39534421..39535461)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (39623125..39624165)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene expressed sequence AW551984 Neighboring gene olfactory receptor family 10 subfamily N member 1 Neighboring gene olfactory receptor family 10 subfamily D member 4C Neighboring gene olfactory receptor family 10 subfamily N member 8, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. In vivo identification of eugenol-responsive and muscone-responsive mouse odorant receptors. McClintock TS, et al. J Neurosci, 2014 Nov 19. PMID 25411495, Free PMC Article
    2. Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse. Xie SY, et al. Mamm Genome, 2000 Dec. PMID 11130974
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor family 10 subfamily D member 4B
    Names
    GA_x6K02T2PVTD-33320043-33320987
    olfactory receptor 960
    olfactory receptor MOR224-12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146279.1 → NP_666391.1  olfactory receptor family 10 subfamily D member 4B

      See identical proteins and their annotated locations for NP_666391.1

      Status: PROVISIONAL

      Source sequence(s)
      AY073814
      Consensus CDS
      CCDS23054.1
      UniProtKB/TrEMBL
      Q8VET5, Q9EQ85
      Related
      ENSMUSP00000076315.3, ENSMUST00000077060.3
      Conserved Domains (2) summary
      pfam00001
      Location:48 → 288
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31 → 306
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      39534421..39535461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313388.1 → XP_017168877.1  olfactory receptor family 10 subfamily D member 4B isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:26 → 52
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 173
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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