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    Actbl2 actin, beta-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 238880, updated on 9-Dec-2024

    Summary

    Official Symbol
    Actbl2provided by MGI
    Official Full Name
    actin, beta-like 2provided by MGI
    Primary source
    MGI:MGI:2444552
    See related
    Ensembl:ENSMUSG00000055194 AllianceGenome:MGI:2444552
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4732495G21Rik
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to be involved in axonogenesis and cell motility. Is active in glutamatergic synapse. Orthologous to human ACTBL2 (actin beta like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Actbl2 in Genome Data Viewer
    Location:
    13 D2.2; 13 63.1 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (111391547..111394283)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (111255013..111257749)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene SCAN domain containing 3 pseudogene Neighboring gene RIKEN cDNA 3110015C05 gene Neighboring gene STARR-seq mESC enhancer starr_35651 Neighboring gene electron transfer flavoprotein subunit alpha, mitochondrial pseudogene Neighboring gene GC-rich promoter binding protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E2421 Neighboring gene STARR-positive B cell enhancer ABC_E1468

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding  
    enables protein kinase binding  
    enables structural constituent of postsynaptic actin cytoskeleton  
    Process Evidence Code Pubs
    involved_in axonogenesis  
    involved_in cell motility  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex  
    is_active_in actin cytoskeleton  
    is_active_in actin filament  
    is_active_in axon  
    is_active_in cytoplasm  
    located_in cytoplasm  
    located_in cytoskeleton  
    is_active_in glutamatergic synapse PubMed 
    is_active_in glutamatergic synapse  
    is_active_in glutamatergic synapse PubMed 
    is_active_in membrane  
    is_active_in synapse PubMed 
    is_active_in synapse PubMed 

    General protein information

    Preferred Names
    beta-actin-like protein 2
    Names
    kappa-actin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175497.3NP_780706.1  beta-actin-like protein 2

      See identical proteins and their annotated locations for NP_780706.1

      Status: PROVISIONAL

      Source sequence(s)
      AK029110
      Consensus CDS
      CCDS26768.1
      UniProtKB/Swiss-Prot
      Q8BFZ3
      UniProtKB/TrEMBL
      Q3U5R4, Q3UA89, Q3UAF7, Q3UGS0, Q61276
      Related
      ENSMUSP00000052086.4, ENSMUST00000054716.4
      Conserved Domains (2) summary
      smart00268
      Location:7376
      ACTIN; Actin
      cl17037
      Location:1376
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      111391547..111394283
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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