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    Nop14 NOP14 nucleolar protein [ Mus musculus (house mouse) ]

    Gene ID: 75416, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nop14provided by MGI
    Official Full Name
    NOP14 nucleolar proteinprovided by MGI
    Primary source
    MGI:MGI:1922666
    See related
    Ensembl:ENSMUSG00000036693 AllianceGenome:MGI:1922666
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nol14; 2610033H07Rik
    Summary
    Predicted to enable enzyme binding activity and snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleoplasm. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; central nervous system; ganglia; lower urinary tract; and sensory organ. Orthologous to human NOP14 (NOP14 nucleolar protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 21.6), CNS E11.5 (RPKM 11.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nop14 in Genome Data Viewer
    Location:
    5 B2; 5 17.91 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (34795880..34817566, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (34638536..34660148, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12845 Neighboring gene microRNA 7036b Neighboring gene adducin 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:34979450-34979637 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:35002815-35002998 Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene predicted gene 15522 Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene microRNA 467g Neighboring gene STARR-positive B cell enhancer ABC_E1050 Neighboring gene huntingtin

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables snoRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Noc4p-Nop14p complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nucleolar protein 14
    Names
    NOP14 nucleolar protein homolog
    nucleolar complex protein 14
    probable nucleolar complex protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029278.3NP_083554.2  nucleolar protein 14

      See identical proteins and their annotated locations for NP_083554.2

      Status: VALIDATED

      Source sequence(s)
      AC115695, AC151669
      Consensus CDS
      CCDS19218.1
      UniProtKB/Swiss-Prot
      Q5RL78, Q8R3N1
      UniProtKB/TrEMBL
      Q3TSX5
      Related
      ENSMUSP00000038382.10, ENSMUST00000041364.13
      Conserved Domains (1) summary
      pfam04147
      Location:24849
      Nop14; Nop14-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      34795880..34817566 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_376833.5 RNA Sequence