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    MTA2 metastasis associated 1 family member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718772, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MTA2provided by VGNC
    Official Full Name
    metastasis associated 1 family member 2provided by VGNC
    Primary source
    VGNC:VGNC:74943
    Locus tag
    EGK_06112
    See related
    Ensembl:ENSMMUG00000018110
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MTA2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (11601850..11610937)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (11711054..11719853)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene beta-1,3-glucuronyltransferase 3 Neighboring gene retinal outer segment membrane protein 1 Neighboring gene EMAP like 3 Neighboring gene uncharacterized LOC106993212 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene uncharacterized LOC106993211 Neighboring gene eukaryotic translation elongation factor 1 gamma

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NuRD complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metastasis-associated protein MTA2
    Names
    Metastasis-associated 1-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266061.1 → NP_001252990.1  metastasis-associated protein MTA2

      See identical proteins and their annotated locations for NP_001252990.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048690
      UniProtKB/TrEMBL
      A0A8J8YB28, F7EC89, G7NCT9, I0FWD5
      Related
      ENSMMUP00000065614.1, ENSMMUT00000107304.1
      Conserved Domains (6) summary
      cd11661
      Location:267 → 312
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      smart00401
      Location:363 → 414
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      PHA03247
      Location:405 → 664
      PHA03247; large tegument protein UL36; Provisional
      cd04709
      Location:3 → 168
      BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
      pfam01448
      Location:147 → 198
      ELM2; ELM2 domain
      pfam17226
      Location:449 → 524
      MTA_R1; MTA R1 domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      11601850..11610937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832862.1 → XP_028688695.1  metastasis-associated protein MTA2 isoform X1

      Conserved Domains (4) summary
      cd11661
      Location:94 → 139
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      smart00401
      Location:190 → 241
      ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
      pfam01448
      Location:1 → 25
      ELM2; ELM2 domain
      pfam17226
      Location:276 → 351
      MTA_R1; MTA R1 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials