U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    HRH2 histamine receptor H2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695226, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    HRH2provided by VGNC
    Official Full Name
    histamine receptor H2provided by VGNC
    Primary source
    VGNC:VGNC:73523
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HRH2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (173083262..173136431)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (174025695..174078851)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene sideroflexin 1 Neighboring gene uncharacterized LOC114678978 Neighboring gene U6 spliceosomal RNA Neighboring gene complexin 2 Neighboring gene THO complex subunit 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Histamine receptors of cones and horizontal cells in Old World monkey retinas. Vila A, et al. J Comp Neurol, 2012 Feb 15. PMID 21800315, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Histamine H2 receptor mRNA is localized in cone inner segments from retina.
      Title: Histamine receptors of cones and horizontal cells in Old World monkey retinas.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histamine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables neurotransmitter receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gastric acid secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histamine H2 receptor

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001198697.3 → NP_001185626.1  histamine H2 receptor

      See identical proteins and their annotated locations for NP_001185626.1

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000388
      UniProtKB/TrEMBL
      F7C4E6, I2CTQ5
      Conserved Domains (1) summary
      pfam00001
      Location:35 → 288
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      173083262..173136431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141438.2 → XP_014996924.1  histamine H2 receptor isoform X1

      UniProtKB/TrEMBL
      A0A1D5QEW1
      Conserved Domains (1) summary
      cd15051
      Location:19 → 299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_028849080.1 → XP_028704913.1  histamine H2 receptor isoform X2

      UniProtKB/TrEMBL
      F7C4E6
      Conserved Domains (1) summary
      cd15051
      Location:19 → 299
      7tmA_Histamine_H2R; histamine subtype H2 receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    RNA

    1. XR_001445669.2 RNA Sequence

    2. XR_001445668.2 RNA Sequence

    3. XR_003730066.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.