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    IQSEC2 IQ motif and Sec7 domain ArfGEF 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702562, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IQSEC2provided by VGNC
    Official Full Name
    IQ motif and Sec7 domain ArfGEF 2provided by VGNC
    Primary source
    VGNC:VGNC:73676
    See related
    Ensembl:ENSMMUG00000020555
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IQSEC2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (52968867..53059489, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (52642240..52734763, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106995211 Neighboring gene actin, cytoplasmic 2-like Neighboring gene uncharacterized LOC114675065 Neighboring gene lysine demethylase 5C Neighboring gene 40S ribosomal protein SA-like Neighboring gene structural maintenance of chromosomes 1A Neighboring gene RIB43A domain with coiled-coils 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    IQ motif and SEC7 domain-containing protein 2
    Names
    IQ motif and SEC7 domain-containing protein 2-like
    IQ motif and Sec7 domain 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      52968867..53059489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127485.2 → XP_014982971.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QE91
      Related
      ENSMMUP00000046360.2, ENSMMUT00000056881.2
      Conserved Domains (4) summary
      pfam01369
      Location:753 → 941
      Sec7; Sec7 domain
      pfam08614
      Location:23 → 64
      ATG16; Autophagy protein 16 (ATG16)
      pfam16453
      Location:961 → 1098
      IQ_SEC7_PH; PH domain
      cl41729
      Location:1318 → 1425
      KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

    2. XM_028842434.1 → XP_028698267.1  IQ motif and SEC7 domain-containing protein 2 isoform X3

      Conserved Domains (2) summary
      pfam16453
      Location:744 → 873
      IQ_SEC7_PH; PH domain
      pfam01369
      Location:533 → 721
      Sec7; Sec7 domain

    3. XM_028842433.1 → XP_028698266.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

      Conserved Domains (2) summary
      pfam16453
      Location:764 → 893
      IQ_SEC7_PH; PH domain
      pfam01369
      Location:553 → 741
      Sec7; Sec7 domain

    4. XM_015127490.2 → XP_014982976.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

      Conserved Domains (2) summary
      pfam01369
      Location:548 → 736
      Sec7; Sec7 domain
      pfam16453
      Location:756 → 893
      IQ_SEC7_PH; PH domain

    5. XM_015127488.2 → XP_014982974.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

      Conserved Domains (3) summary
      pfam01369
      Location:527 → 715
      Sec7; Sec7 domain
      pfam16453
      Location:735 → 872
      IQ_SEC7_PH; PH domain
      cl41729
      Location:1092 → 1199
      KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

    6. XM_028842435.1 → XP_028698268.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

      Conserved Domains (4) summary
      PRK13709
      Location:233 → 377
      PRK13709; conjugal transfer nickase/helicase TraI; Provisional
      pfam16453
      Location:964 → 1093
      IQ_SEC7_PH; PH domain
      pfam01369
      Location:753 → 941
      Sec7; Sec7 domain
      pfam08614
      Location:23 → 64
      ATG16; Autophagy protein 16 (ATG16)

    7. XM_001086079.4 → XP_001086079.1  IQ motif and SEC7 domain-containing protein 2 isoform X7

      See identical proteins and their annotated locations for XP_001086079.1

    Nucleotide Protein
    Heading Accession and Version

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