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    PHF8 PHD finger protein 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703633, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PHF8provided by VGNC
    Official Full Name
    PHD finger protein 8provided by VGNC
    Primary source
    VGNC:VGNC:75836
    See related
    Ensembl:ENSMMUG00000008751
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PHF8 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (53664032..53772630, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (53353565..53461477, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene 39S ribosomal protein L32, mitochondrial pseudogene Neighboring gene 28S ribosomal protein S18c, mitochondrial pseudogene Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene family with sequence similarity 120 member C Neighboring gene WNK lysine deficient protein kinase 3 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone demethylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein demethylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone lysine demethylase PHF8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      53664032..53772630 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127505.2 → XP_014982991.1  histone lysine demethylase PHF8 isoform X3

      UniProtKB/TrEMBL
      H9FRR4
      Conserved Domains (3) summary
      smart00558
      Location:235 → 298
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cd15642
      Location:42 → 93
      PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
      cl21464
      Location:270 → 370
      cupin_like; Conserved domain found in cupin and related proteins

    2. XM_015127501.2 → XP_014982987.1  histone lysine demethylase PHF8 isoform X1

      UniProtKB/TrEMBL
      F7DQV4, H9Z1P6
      Related
      ENSMMUP00000011477.4, ENSMMUT00000012236.4
      Conserved Domains (3) summary
      smart00558
      Location:235 → 298
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cd15642
      Location:42 → 93
      PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
      cl21464
      Location:270 → 370
      cupin_like; Conserved domain found in cupin and related proteins

    3. XM_015127504.2 → XP_014982990.1  histone lysine demethylase PHF8 isoform X2

      UniProtKB/TrEMBL
      F7DQV4, F7DQX0, H9Z1P6
      Related
      ENSMMUP00000011475.3, ENSMMUT00000012234.4
      Conserved Domains (4) summary
      smart00558
      Location:199 → 262
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cd15642
      Location:6 → 57
      PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
      pfam17811
      Location:338 → 441
      JHD; Jumonji helical domain
      cl40423
      Location:234 → 334
      cupin_RmlC-like; RmlC-like cupin superfamily

    4. XM_015127502.2 → XP_014982988.1  histone lysine demethylase PHF8 isoform X2

      UniProtKB/TrEMBL
      F7DQV4, F7DQX0, H9Z1P6
      Related
      ENSMMUP00000071060.1, ENSMMUT00000093471.1
      Conserved Domains (4) summary
      smart00558
      Location:199 → 262
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cd15642
      Location:6 → 57
      PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
      pfam17811
      Location:338 → 441
      JHD; Jumonji helical domain
      cl40423
      Location:234 → 334
      cupin_RmlC-like; RmlC-like cupin superfamily

    5. XM_015127506.2 → XP_014982992.1  histone lysine demethylase PHF8 isoform X4

      UniProtKB/TrEMBL
      H9FRR4
      Related
      ENSMMUP00000079668.1, ENSMMUT00000082202.1
      Conserved Domains (4) summary
      smart00558
      Location:199 → 262
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cd15642
      Location:6 → 57
      PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
      pfam02373
      Location:234 → 334
      JmjC; JmjC domain, hydroxylase
      pfam17811
      Location:338 → 441
      JHD; Jumonji helical domain
    Nucleotide Protein
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