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    OAS1 2'-5'-oligoadenylate synthetase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712265, updated on 17-Aug-2024

    Summary

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    Official Symbol
    OAS1provided by VGNC
    Official Full Name
    2'-5'-oligoadenylate synthetase 1provided by VGNC
    Primary source
    VGNC:VGNC:75570
    See related
    Ensembl:ENSMMUG00000012782
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See OAS1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (112632314..112654759)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (112949175..112971674)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671076 Neighboring gene rabphilin 3A Neighboring gene 2'-5'-oligoadenylate synthetase 3 Neighboring gene 2'-5'-oligoadenylate synthetase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2'-5'-oligoadenylate synthetase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of viral genome replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    2'-5'-oligoadenylate synthase 1
    Names
    2'-5' oligoadenylate stnthetase 1
    2'-5'-oligoadenylate synthetase 1, 40/46kDa
    NP_001077418.1
    XP_015008328.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083949.1 → NP_001077418.1  2'-5'-oligoadenylate synthase 1

      See identical proteins and their annotated locations for NP_001077418.1

      Status: PROVISIONAL

      Source sequence(s)
      EF467666
      UniProtKB/TrEMBL
      A4LA99, A4LAA0
      Related
      ENSMMUP00000016793.4, ENSMMUT00000017932.4
      Conserved Domains (2) summary
      cd05400
      Location:29 → 166
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:163 → 343
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      112632314..112654759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152842.2 → XP_015008328.2  2'-5'-oligoadenylate synthase 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZSP7
      Related
      ENSMMUP00000068674.1, ENSMMUT00000081471.1
      Conserved Domains (2) summary
      cd05400
      Location:117 → 254
      NT_2-5OAS_ClassI-CCAase; Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme
      pfam10421
      Location:252 → 431
      OAS1_C; 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
    Nucleotide Protein
    Heading Accession and Version

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