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    APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702084, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APEX2provided by VGNC
    Official Full Name
    apurinic/apyrimidinic endodeoxyribonuclease 2provided by VGNC
    Primary source
    VGNC:VGNC:69857
    See related
    Ensembl:ENSMMUG00000008428
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See APEX2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (54727151..54734404)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (54418794..54426047)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA11 Neighboring gene trophinin Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene replication protein A 70 kDa DNA-binding subunit pseudogene Neighboring gene PAGE family member 2B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables double-stranded DNA 3'-5' DNA exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in base-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-(apurinic or apyrimidinic site) endonuclease 2
    Names
    DNA-(apurinic or apyrimidinic site) lyase 2
    NP_001248294.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261365.1 → NP_001248294.1  DNA-(apurinic or apyrimidinic site) endonuclease 2

      See identical proteins and their annotated locations for NP_001248294.1

      Status: PROVISIONAL

      Source sequence(s)
      JV045278
      UniProtKB/TrEMBL
      F6VBU4, G7NRI7
      Related
      ENSMMUP00000011049.2, ENSMMUT00000011782.4
      Conserved Domains (2) summary
      cd09088
      Location:3 → 311
      Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
      pfam06839
      Location:467 → 514
      zf-GRF; GRF zinc finger

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      54727151..54734404
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials