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    ADAM10 ADAM metallopeptidase domain 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701355, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAM10provided by VGNC
    Official Full Name
    ADAM metallopeptidase domain 10provided by VGNC
    Primary source
    VGNC:VGNC:69465
    See related
    Ensembl:ENSMMUG00000017507
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAM10 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (35002933..35159892, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (35149252..35302292, complement)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114679419 Neighboring gene lipase C, hepatic type Neighboring gene small nucleolar RNA U13 Neighboring gene putative heat shock protein HSP 90-beta 4 Neighboring gene small nucleolar RNA U3 Neighboring gene MINDY lysine 48 deubiquitinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity involved in amyloid precursor protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in membrane protein ectodomain proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disintegrin and metalloproteinase domain-containing protein 10
    XP_001097016.2
    XP_028706819.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      35002933..35159892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001097016.4 → XP_001097016.2  disintegrin and metalloproteinase domain-containing protein 10 isoform X1

      UniProtKB/TrEMBL
      F6V4A7, G7MXJ7, H9EQI5
      Related
      ENSMMUP00000064836.1, ENSMMUT00000085071.1
      Conserved Domains (3) summary
      smart00050
      Location:466 → 545
      DISIN; Homologues of snake disintegrins
      cd04270
      Location:220 → 459
      ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
      pfam01562
      Location:46 → 156
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_028850986.1 → XP_028706819.1  disintegrin and metalloproteinase domain-containing protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QFJ7, G7MXJ7
      Related
      ENSMMUP00000046817.2, ENSMMUT00000077486.2
      Conserved Domains (3) summary
      smart00050
      Location:392 → 471
      DISIN; Homologues of snake disintegrins
      cd04270
      Location:146 → 385
      ZnMc_TACE_like; Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha.
      pfam01562
      Location:2 → 82
      Pep_M12B_propep; Reprolysin family propeptide
    Nucleotide Protein
    Heading Accession and Version

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