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    SCN10A sodium voltage-gated channel alpha subunit 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694962, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SCN10Aprovided by VGNC
    Official Full Name
    sodium voltage-gated channel alpha subunit 10provided by VGNC
    Primary source
    VGNC:VGNC:76980
    See related
    Ensembl:ENSMMUG00000015827
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SCN10A in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (94148431..94249430, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (103931004..104032071)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L18a pseudogene Neighboring gene sodium voltage-gated channel alpha subunit 5 Neighboring gene uncharacterized LOC106996957 Neighboring gene sodium voltage-gated channel alpha subunit 11 Neighboring gene uncharacterized LOC106996956 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in AV node cell action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of atrial cardiac muscle cell membrane depolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of heart rate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 10 subunit alpha
    Names
    sodium channel protein type 10 subunit alpha-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      94148431..94249430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015131317.2 → XP_014986803.2  sodium channel protein type 10 subunit alpha isoform X3

      UniProtKB/TrEMBL
      F7CEK9
      Conserved Domains (4) summary
      cd13433
      Location:1324 → 1376
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1056 → 1332
      Ion_trans; Ion transport protein
      pfam06512
      Location:809 → 1052
      Na_trans_assoc; Sodium ion transport-associated
      pfam16905
      Location:1641 → 1704
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    2. XM_015131316.2 → XP_014986802.2  sodium channel protein type 10 subunit alpha isoform X2

      UniProtKB/TrEMBL
      F7CEK9
      Conserved Domains (5) summary
      cd13433
      Location:1421 → 1473
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1153 → 1429
      Ion_trans; Ion transport protein
      pfam06512
      Location:907 → 1149
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:459 → 608
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1738 → 1801
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated

    3. XM_015131314.2 → XP_014986800.2  sodium channel protein type 10 subunit alpha isoform X1

      UniProtKB/TrEMBL
      F7CEK9
      Related
      ENSMMUP00000020805.4, ENSMMUT00000022236.4
      Conserved Domains (5) summary
      cd13433
      Location:1422 → 1474
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1154 → 1430
      Ion_trans; Ion transport protein
      pfam06512
      Location:907 → 1150
      Na_trans_assoc; Sodium ion transport-associated
      pfam11933
      Location:459 → 608
      Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
      pfam16905
      Location:1739 → 1802
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
    Heading Accession and Version

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