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    IL2RG interleukin 2 receptor subunit gamma [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 641338, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IL2RGprovided by VGNC
    Official Full Name
    interleukin 2 receptor subunit gammaprovided by VGNC
    Primary source
    VGNC:VGNC:111899
    Locus tag
    EGK_20620
    See related
    Ensembl:ENSMMUG00000017795
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See IL2RG in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (68094579..68105451, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (65838411..65849196, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene forkhead box O4 Neighboring gene chromosome X CXorf65 homolog Neighboring gene mediator complex subunit 12 Neighboring gene neuroligin 3 Neighboring gene gap junction protein beta 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rapid down-regulation of γc on T cells in early SIV infection correlates with impairment of T-cell function. Xu H, et al. FASEB J, 2012 Jun. PMID 22375017, Free PMC Article
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytokine receptor common subunit gamma
    Names
    interleukin 2 receptor, gamma (severe combined immunodeficiency)
    membrane receptor Il2rg

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035529.1 → NP_001030606.1  cytokine receptor common subunit gamma precursor

      See identical proteins and their annotated locations for NP_001030606.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ222417
      UniProtKB/TrEMBL
      A0A5F8A3G1, A0A8J8XU62, F7E1B5, G7NRV1, Q38JL2
      Related
      ENSMMUP00000072462.1, ENSMMUT00000106990.1
      Conserved Domains (2) summary
      cd00063
      Location:154 → 246
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:59 → 151
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      68094579..68105451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028841644.1 → XP_028697477.1  cytokine receptor common subunit gamma isoform X2

      UniProtKB/TrEMBL
      A0A5F8A3G1
      Conserved Domains (2) summary
      cd00063
      Location:110 → 202
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:15 → 107
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    2. XM_015127637.2 → XP_014983123.1  cytokine receptor common subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A5F8A3G1, A0A8J8XU62, F7E1B5, G7NRV1, Q38JL2
      Related
      ENSMMUP00000023402.4, ENSMMUT00000025011.4
      Conserved Domains (2) summary
      cd00063
      Location:154 → 246
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:59 → 151
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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