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    DOCK2 dedicator of cytokinesis 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704061, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DOCK2provided by VGNC
    Official Full Name
    dedicator of cytokinesis 2provided by VGNC
    Primary source
    VGNC:VGNC:71966
    See related
    Ensembl:ENSMMUG00000009366
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DOCK2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (167047668..167489347)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (167911800..168345126)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene spindle apparatus coiled-coil protein 1 Neighboring gene inhibitory synaptic factor family member 2B Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene forkhead box I1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dedicator of cytokinesis protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      167047668..167489347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849910.1 → XP_028705743.1  dedicator of cytokinesis protein 2 isoform X2

      UniProtKB/TrEMBL
      G7MVV3
      Conserved Domains (4) summary
      cd11706
      Location:1200 → 1620
      DHR2_DOCK2; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 2
      cd12050
      Location:12 → 67
      SH3_DOCK2_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis protein 2
      pfam16172
      Location:71 → 414
      DOCK_N; DOCK N-terminus
      cl14603
      Location:422 → 617
      C2; C2 domain

    2. XM_028849908.1 → XP_028705741.1  dedicator of cytokinesis protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A215, G7MVV3
      Related
      ENSMMUP00000070936.1, ENSMMUT00000090173.1
      Conserved Domains (4) summary
      cd11706
      Location:1200 → 1620
      DHR2_DOCK2; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 2
      cd12050
      Location:12 → 67
      SH3_DOCK2_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis protein 2
      pfam16172
      Location:71 → 414
      DOCK_N; DOCK N-terminus
      cl14603
      Location:422 → 617
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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