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    TYRO3 TYRO3 protein tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710902, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TYRO3provided by VGNC
    Official Full Name
    TYRO3 protein tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:78683
    See related
    Ensembl:ENSMMUG00000013803
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TYRO3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (18020975..18045059)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (17929967..17954598)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene leukocyte receptor tyrosine kinase Neighboring gene RNA polymerase II associated protein 1 Neighboring gene MAX dimerization protein MGA Neighboring gene microRNA mir-626 Neighboring gene 40S ribosomal protein S15a pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in platelet aggregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase receptor TYRO3
    XP_014997475.1
    XP_028706598.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      18020975..18045059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141989.2 → XP_014997475.1  tyrosine-protein kinase receptor TYRO3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QZU0, F6T717, H9ESJ0
      Related
      ENSMMUP00000018152.4, ENSMMUT00000019382.4
      Conserved Domains (7) summary
      cd05749
      Location:141 → 220
      Ig2_Tyro3_like; Second immunoglobulin (Ig)-like domain of Axl/Tyro3 receptor tyrosine kinases (RTKs)
      smart00408
      Location:56 → 121
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:49 → 135
      IG_like; Immunoglobulin like
      cd00063
      Location:225 → 317
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05074
      Location:508 → 791
      PTKc_Tyro3; Catalytic domain of the Protein Tyrosine Kinase, Tyro3
      pfam00041
      Location:324 → 406
      fn3; Fibronectin type III domain
      pfam07714
      Location:518 → 786
      Pkinase_Tyr; Protein tyrosine kinase

    2. XM_028850765.1 → XP_028706598.1  tyrosine-protein kinase receptor TYRO3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QZU0
      Related
      ENSMMUP00000077816.1, ENSMMUT00000100574.1
      Conserved Domains (5) summary
      cd05749
      Location:96 → 175
      Ig2_Axl_Tyro3_like; Second immunoglobulin (Ig)-like domain of Axl/Tyro3 family receptor tyrosine kinases (RTKs)
      smart00408
      Location:11 → 76
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:180 → 272
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05074
      Location:463 → 746
      PTKc_Tyro3; Catalytic domain of the Protein Tyrosine Kinase, Tyro3
      pfam00041
      Location:279 → 360
      fn3; Fibronectin type III domain
    Nucleotide Protein
    Heading Accession and Version

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