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    SH3PXD2A SH3 and PX domains 2A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714868, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SH3PXD2Aprovided by VGNC
    Official Full Name
    SH3 and PX domains 2Aprovided by VGNC
    Primary source
    VGNC:VGNC:77297
    See related
    Ensembl:ENSMMUG00000007067
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SH3PXD2A in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (104153815..104410331, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (99412372..99668792, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene calcium homeostasis modulator 1 Neighboring gene calcium homeostasis modulator 3 Neighboring gene neuralized E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC114670031 Neighboring gene uncharacterized LOC114670143 Neighboring gene STN1 subunit of CST complex

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables superoxide-generating NADPH oxidase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH3 and PX domain-containing protein 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      104153815..104410331 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015148096.2 → XP_015003582.1  SH3 and PX domain-containing protein 2A isoform X2

      UniProtKB/TrEMBL
      H9F749
      Conserved Domains (6) summary
      cd06888
      Location:6 → 124
      PX_FISH; The phosphoinositide binding Phox Homology domain of Five SH protein
      cd12019
      Location:829 → 881
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:1061 → 1117
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:155 → 207
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:254 → 307
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:436 → 489
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains

    2. XM_015148097.2 → XP_015003583.1  SH3 and PX domain-containing protein 2A isoform X3

      UniProtKB/TrEMBL
      F7EWT0, H9F749
      Related
      ENSMMUP00000009262.3, ENSMMUT00000009867.4
      Conserved Domains (6) summary
      cd06888
      Location:6 → 124
      PX_FISH; The phosphoinositide binding Phox Homology domain of Five SH protein
      cd12019
      Location:816 → 868
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:1048 → 1104
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:170 → 222
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:241 → 294
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:423 → 476
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains

    3. XM_015148095.2 → XP_015003581.1  SH3 and PX domain-containing protein 2A isoform X1

      UniProtKB/TrEMBL
      H9F749
      Conserved Domains (6) summary
      cd06888
      Location:6 → 124
      PX_FISH; The phosphoinositide binding Phox Homology domain of Five SH protein
      cd12019
      Location:844 → 896
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:1076 → 1132
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:170 → 222
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:269 → 322
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:451 → 504
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains

    4. XM_028826811.1 → XP_028682644.1  SH3 and PX domain-containing protein 2A isoform X6

      UniProtKB/TrEMBL
      H9F749
      Conserved Domains (6) summary
      cd12019
      Location:725 → 777
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:957 → 1013
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:51 → 103
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:150 → 203
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:332 → 385
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      TIGR04211
      Location:741 → 826
      SH3_and_anchor; SH3 domain protein

    5. XM_028826809.1 → XP_028682642.1  SH3 and PX domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A1D5QSZ0, H9F749
      Related
      ENSMMUP00000051168.2, ENSMMUT00000068030.2
      Conserved Domains (6) summary
      cd12019
      Location:679 → 731
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:911 → 967
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12074
      Location:5 → 57
      SH3_Tks5_1; First Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:104 → 157
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:286 → 339
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      TIGR04211
      Location:695 → 780
      SH3_and_anchor; SH3 domain protein

    6. XM_015148098.2 → XP_015003584.1  SH3 and PX domain-containing protein 2A isoform X4

      UniProtKB/TrEMBL
      A0A1D5RGH6, F7EWU2
      Related
      ENSMMUP00000059420.1, ENSMMUT00000069427.2
      Conserved Domains (5) summary
      cd12019
      Location:714 → 766
      SH3_Tks5_4; Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12020
      Location:946 → 1002
      SH3_Tks5_5; Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12077
      Location:139 → 192
      SH3_Tks5_2; Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      cd12079
      Location:321 → 374
      SH3_Tks5_3; Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains
      pfam02993
      Location:203 → 355
      MCPVI; Minor capsid protein VI
    Nucleotide Protein
    Heading Accession and Version

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