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    ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707778, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS1provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 1provided by VGNC
    Primary source
    VGNC:VGNC:80327
    Locus tag
    EGK_13346
    See related
    Ensembl:ENSMMUG00000013407
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (19828708..19837772)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (20090223..20099291)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997280 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 5 Neighboring gene uncharacterized LOC114676830 Neighboring gene small integral membrane protein 26-like Neighboring gene cysteine and tyrosine rich 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 1
    NP_001253193.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266264.1 → NP_001253193.1  A disintegrin and metalloproteinase with thrombospondin motifs 1

      See identical proteins and their annotated locations for NP_001253193.1

      Status: PROVISIONAL

      Source sequence(s)
      JU321572
      UniProtKB/TrEMBL
      A0A5F7ZE35, A0A5S6RCC6, A0A8J8XNF4, F6Z3Q2, G7MNA9
      Related
      ENSMMUP00000017609.4, ENSMMUT00000018804.4
      Conserved Domains (6) summary
      smart00209
      Location:562 → 614
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:258 → 463
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam01421
      Location:258 → 467
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:66 → 166
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:725 → 842
      ADAM_spacer1; ADAM-TS Spacer 1
      cl15456
      Location:468 → 548
      ADAM_CR; ADAM cysteine-rich

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      19828708..19837772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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