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    HELZ helicase with zinc finger [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718729, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HELZprovided by VGNC
    Official Full Name
    helicase with zinc fingerprovided by VGNC
    Primary source
    VGNC:VGNC:73178
    Locus tag
    EGK_08900
    See related
    Ensembl:ENSMMUG00000002959
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HELZ in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (63454989..63632664, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (60543656..60721014, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 4 Neighboring gene uncharacterized LOC100424173 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 1 Neighboring gene 60S ribosomal protein L36a-like Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC106994106 Neighboring gene zinc finger protein 714-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulatory ncRNA-mediated post-transcriptional gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P granule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable helicase with zinc finger domain
    Names
    probable helicase with zinc finger domain-like
    putative helicase with zinc finger domain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      63454989..63632664 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015120164.2 → XP_014975650.1  probable helicase with zinc finger domain isoform X1

      UniProtKB/TrEMBL
      F7GZQ1
      Conserved Domains (5) summary
      cl25932
      Location:1629 → 1788
      Peptidase_S21; Assemblin (Peptidase family S21)
      cd18077
      Location:641 → 868
      DEXXQc_HELZ; DEXXQ-box helicase domain of HELZ
      pfam00642
      Location:181 → 205
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam03154
      Location:1178 → 1389
      Atrophin-1; Atrophin-1 family
      pfam13087
      Location:841 → 1052
      AAA_12; AAA domain

    2. XM_015120166.2 → XP_014975652.1  probable helicase with zinc finger domain isoform X1

      UniProtKB/TrEMBL
      F7GZQ1
      Conserved Domains (5) summary
      cl25932
      Location:1629 → 1788
      Peptidase_S21; Assemblin (Peptidase family S21)
      cd18077
      Location:641 → 868
      DEXXQc_HELZ; DEXXQ-box helicase domain of HELZ
      pfam00642
      Location:181 → 205
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam03154
      Location:1178 → 1389
      Atrophin-1; Atrophin-1 family
      pfam13087
      Location:841 → 1052
      AAA_12; AAA domain

    3. XM_015120165.2 → XP_014975651.1  probable helicase with zinc finger domain isoform X1

      UniProtKB/TrEMBL
      F7GZQ1
      Conserved Domains (5) summary
      cl25932
      Location:1629 → 1788
      Peptidase_S21; Assemblin (Peptidase family S21)
      cd18077
      Location:641 → 868
      DEXXQc_HELZ; DEXXQ-box helicase domain of HELZ
      pfam00642
      Location:181 → 205
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam03154
      Location:1178 → 1389
      Atrophin-1; Atrophin-1 family
      pfam13087
      Location:841 → 1052
      AAA_12; AAA domain

    4. XM_015120168.2 → XP_014975654.1  probable helicase with zinc finger domain isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZMN6, A0A8J8XVZ1, F7BIR8, F7GZQ1, G7NJB3
      Related
      ENSMMUP00000066882.1, ENSMMUT00000085937.1
      Conserved Domains (5) summary
      cl25932
      Location:1628 → 1787
      Peptidase_S21; Assemblin (Peptidase family S21)
      cd18077
      Location:641 → 867
      DEXXQc_HELZ; DEXXQ-box helicase domain of HELZ
      pfam00642
      Location:181 → 205
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam03154
      Location:1177 → 1388
      Atrophin-1; Atrophin-1 family
      pfam13087
      Location:840 → 1051
      AAA_12; AAA domain
    Nucleotide Protein
    Heading Accession and Version

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