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    TINAG tubulointerstitial nephritis antigen [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711185, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TINAGprovided by VGNC
    Official Full Name
    tubulointerstitial nephritis antigenprovided by VGNC
    Primary source
    VGNC:VGNC:78382
    See related
    Ensembl:ENSMMUG00000012784
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TINAG in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (115150146..115233674, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (55343127..55428832)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L10-like Neighboring gene methylosome subunit pICln pseudogene Neighboring gene uncharacterized LOC114677584 Neighboring gene muscular LMNA interacting protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tubulointerstitial nephritis antigen

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      115150146..115233674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028847472.1 → XP_028703305.1  tubulointerstitial nephritis antigen isoform X5

      Conserved Domains (3) summary
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain
      cl17735
      Location:120 → 167
      VWC; von Willebrand factor type C domain
      cl23744
      Location:218 → 399
      Peptidase_C1; C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some ...

    2. XM_015136583.2 → XP_014992069.1  tubulointerstitial nephritis antigen isoform X3

      UniProtKB/TrEMBL
      G7MPM5
      Conserved Domains (2) summary
      cd02620
      Location:168 → 440
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain

    3. XM_015136584.2 → XP_014992070.1  tubulointerstitial nephritis antigen isoform X4

      UniProtKB/TrEMBL
      G7MPM5
      Conserved Domains (2) summary
      smart00215
      Location:45 → 92
      VWC_out; von Willebrand factor (vWF) type C domain
      cd02620
      Location:143 → 415
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...

    4. XM_015136581.2 → XP_014992067.1  tubulointerstitial nephritis antigen isoform X1

      UniProtKB/TrEMBL
      G7MPM5
      Conserved Domains (3) summary
      smart00215
      Location:120 → 167
      VWC_out; von Willebrand factor (vWF) type C domain
      cd02620
      Location:218 → 490
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain

    5. XM_015136582.2 → XP_014992068.1  tubulointerstitial nephritis antigen isoform X2

      UniProtKB/TrEMBL
      G7MPM5
      Related
      ENSMMUP00000016796.2, ENSMMUT00000017935.3
      Conserved Domains (3) summary
      smart00215
      Location:120 → 167
      VWC_out; von Willebrand factor (vWF) type C domain
      cd02620
      Location:218 → 465
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain
    Nucleotide Protein
    Heading Accession and Version

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