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    MAST2 microtubule associated serine/threonine kinase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706998, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAST2provided by VGNC
    Official Full Name
    microtubule associated serine/threonine kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:74532
    See related
    Ensembl:ENSMMUG00000015371
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAST2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (178358255..178615134, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (45388316..45646777)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene phosphoinositide-3-kinase regulatory subunit 3 Neighboring gene translation machinery-associated protein 16 pseudogene Neighboring gene intracisternal A particle-promoted polypeptide Neighboring gene transmembrane protein 69

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule-associated serine/threonine-protein kinase 2
    XP_001105315.1
    XP_014994093.1
    XP_014994101.1
    XP_014994106.1
    XP_014994109.1
    XP_014994113.1
    XP_014994120.1
    XP_028690030.1
    XP_028690031.1
    XP_028690032.1
    XP_028690033.1
    XP_028690034.1
    XP_028690035.1
    XP_028690039.1
    XP_028690041.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      178358255..178615134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015138615.2 → XP_014994101.1  microtubule-associated serine/threonine-protein kinase 2 isoform X6

      UniProtKB/TrEMBL
      F6SGA1
      Conserved Domains (4) summary
      smart00220
      Location:512 → 785
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:1105 → 1186
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:511 → 790
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:201 → 475
      DUF1908; Domain of unknown function (DUF1908)

    2. XM_001105315.4 → XP_001105315.1  microtubule-associated serine/threonine-protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      F6SGA1
      Related
      ENSMMUP00000073144.1, ENSMMUT00000081515.1
      Conserved Domains (4) summary
      smart00220
      Location:512 → 785
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:1105 → 1186
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:511 → 790
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:201 → 475
      DUF1908; Domain of unknown function (DUF1908)

    3. XM_015138607.2 → XP_014994093.1  microtubule-associated serine/threonine-protein kinase 2 isoform X4

      UniProtKB/TrEMBL
      F6S9N8, F6SGA1
      Related
      ENSMMUP00000020176.3, ENSMMUT00000021572.4
      Conserved Domains (4) summary
      smart00220
      Location:519 → 792
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:1112 → 1193
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:518 → 797
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:201 → 482
      DUF1908; Domain of unknown function (DUF1908)

    4. XM_028834199.1 → XP_028690032.1  microtubule-associated serine/threonine-protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A5F7ZWR3, F6SGA1
      Related
      ENSMMUP00000069080.1, ENSMMUT00000087751.1
      Conserved Domains (3) summary
      cd00992
      Location:1170 → 1251
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:576 → 855
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:266 → 540
      DUF1908; Domain of unknown function (DUF1908)

    5. XM_028834198.1 → XP_028690031.1  microtubule-associated serine/threonine-protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      F6SGA1
      Conserved Domains (3) summary
      cd00992
      Location:1177 → 1258
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:583 → 862
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:266 → 547
      DUF1908; Domain of unknown function (DUF1908)

    6. XM_028834197.1 → XP_028690030.1  microtubule-associated serine/threonine-protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZDE4, F6SGA1
      Related
      ENSMMUP00000062659.1, ENSMMUT00000097114.1
      Conserved Domains (3) summary
      cd00992
      Location:1177 → 1258
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:583 → 862
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:266 → 547
      DUF1908; Domain of unknown function (DUF1908)

    7. XM_015138634.2 → XP_014994120.1  microtubule-associated serine/threonine-protein kinase 2 isoform X13

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (4) summary
      smart00220
      Location:364 → 637
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:957 → 1038
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:363 → 642
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:46 → 327
      DUF1908; Domain of unknown function (DUF1908)

    8. XM_028834201.1 → XP_028690034.1  microtubule-associated serine/threonine-protein kinase 2 isoform X9

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (3) summary
      cd00992
      Location:1022 → 1103
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:428 → 707
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:111 → 392
      DUF1908; Domain of unknown function (DUF1908)

    9. XM_015138623.2 → XP_014994109.1  microtubule-associated serine/threonine-protein kinase 2 isoform X11

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (4) summary
      smart00220
      Location:376 → 649
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:969 → 1050
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:375 → 654
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:58 → 339
      DUF1908; Domain of unknown function (DUF1908)

    10. XM_028834200.1 → XP_028690033.1  microtubule-associated serine/threonine-protein kinase 2 isoform X7

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (3) summary
      cd00992
      Location:1034 → 1115
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:440 → 719
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:123 → 404
      DUF1908; Domain of unknown function (DUF1908)

    11. XM_028834202.1 → XP_028690035.1  microtubule-associated serine/threonine-protein kinase 2 isoform X10

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (3) summary
      cd00992
      Location:990 → 1071
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:396 → 675
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:86 → 360
      DUF1908; Domain of unknown function (DUF1908)

    12. XM_015138620.2 → XP_014994106.1  microtubule-associated serine/threonine-protein kinase 2 isoform X8

      UniProtKB/TrEMBL
      A0A1D5QG69, F6S9Q5
      Related
      ENSMMUP00000047039.2, ENSMMUT00000078013.2
      Conserved Domains (4) summary
      smart00220
      Location:434 → 707
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:1027 → 1108
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:433 → 712
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:116 → 397
      DUF1908; Domain of unknown function (DUF1908)

    13. XM_015138627.2 → XP_014994113.1  microtubule-associated serine/threonine-protein kinase 2 isoform X12

      UniProtKB/TrEMBL
      F6S9Q5
      Related
      ENSMMUP00000020175.4, ENSMMUT00000021571.4
      Conserved Domains (4) summary
      smart00220
      Location:369 → 642
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:962 → 1043
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:368 → 647
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:51 → 332
      DUF1908; Domain of unknown function (DUF1908)

    14. XM_028834206.1 → XP_028690039.1  microtubule-associated serine/threonine-protein kinase 2 isoform X14

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (3) summary
      cd00992
      Location:922 → 1003
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:328 → 607
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:11 → 292
      DUF1908; Domain of unknown function (DUF1908)

    15. XM_028834208.1 → XP_028690041.1  microtubule-associated serine/threonine-protein kinase 2 isoform X15

      UniProtKB/TrEMBL
      F6S9Q5
      Conserved Domains (3) summary
      cd00992
      Location:915 → 996
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:321 → 600
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:11 → 285
      DUF1908; Domain of unknown function (DUF1908)
    Nucleotide Protein
    Heading Accession and Version

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