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    TLE5 TLE family member 5, transcriptional modulator [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712353, updated on 5-Mar-2024

    Summary

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    Gene symbol
    TLE5
    Gene description
    TLE family member 5, transcriptional modulator
    See related
    Ensembl:ENSMMUG00000002913
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    AES
    Orthologs
    human mouse all
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    Genomic context

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    See TLE5 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (2928189..2938232, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (2990166..2998535, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene TLE family member 2, transcriptional corepressor Neighboring gene G protein subunit alpha 11 Neighboring gene G protein subunit alpha 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amino-terminal enhancer of split

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      2928189..2938232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028839655.1 → XP_028695488.1  amino-terminal enhancer of split isoform X2

      Conserved Domains (1) summary
      pfam03920
      Location:31 → 157
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    2. XM_028839654.1 → XP_028695487.1  amino-terminal enhancer of split isoform X1

      Related
      ENSMMUP00000045601.2, ENSMMUT00000055289.2
      Conserved Domains (1) summary
      pfam03920
      Location:31 → 158
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    3. XM_028839657.1 → XP_028695490.1  amino-terminal enhancer of split isoform X4

      Conserved Domains (1) summary
      pfam03920
      Location:11 → 131
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    4. XM_028839656.1 → XP_028695489.1  amino-terminal enhancer of split isoform X3

      UniProtKB/TrEMBL
      H9FQP9
      Conserved Domains (1) summary
      pfam03920
      Location:11 → 132
      TLE_N; Groucho/TLE N-terminal Q-rich domain

    5. XM_028839658.1 → XP_028695491.1  amino-terminal enhancer of split isoform X5

      Conserved Domains (1) summary
      pfam03920
      Location:1 → 76
      TLE_N; Groucho/TLE N-terminal Q-rich domain
    Nucleotide Protein
    Heading Accession and Version

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