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    MDM4 MDM4 regulator of p53 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699563, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MDM4provided by VGNC
    Official Full Name
    MDM4 regulator of p53provided by VGNC
    Primary source
    VGNC:VGNC:74693
    Locus tag
    EGK_01759
    See related
    Ensembl:ENSMMUG00000011236
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MDM4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (62014296..62064962)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (162040310..162090593, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene peflin pseudogene Neighboring gene leucine rich repeat neuronal 2 Neighboring gene uncharacterized LOC100429512 Neighboring gene uncharacterized LOC114680126

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Mdm4
    Names
    MDM4, p53 regulator
    Mdm4 p53 binding protein homolog
    Mdm4, transformed 3T3 cell double minute 4, p53 binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      62014296..62064962
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028852262.1 → XP_028708095.1  protein Mdm4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RJC8, A0A5S6R9E2, A0A8J8XCI6, G7MEU6, H9EV85, I0FL33
      Related
      ENSMMUP00000014729.4, ENSMMUT00000015723.4
      Conserved Domains (3) summary
      pfam00641
      Location:300 → 329
      zf-RanBP; Zn-finger in Ran binding protein and others
      cd16784
      Location:432 → 490
      mRING-HC-C2H2C4_MDM4; Modified RING finger, HC subclass (C2H2C4-type), found in protein MDM4 and similar proteins
      cd17673
      Location:29 → 107
      MDM4; p53-binding domain found in MDM4 and similar proteins

    2. XM_028852259.1 → XP_028708092.1  protein Mdm4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RJC8, A0A5S6R9E2, A0A8J8XCI6, G7MEU6, H9EV85, I0FL33
      Related
      ENSMMUP00000060422.2, ENSMMUT00000056381.2
      Conserved Domains (3) summary
      pfam00641
      Location:300 → 329
      zf-RanBP; Zn-finger in Ran binding protein and others
      cd16784
      Location:432 → 490
      mRING-HC-C2H2C4_MDM4; Modified RING finger, HC subclass (C2H2C4-type), found in protein MDM4 and similar proteins
      cd17673
      Location:29 → 107
      MDM4; p53-binding domain found in MDM4 and similar proteins

    3. XM_028852266.1 → XP_028708099.1  protein Mdm4 isoform X2

      UniProtKB/TrEMBL
      H9EV85, I0FL33
      Conserved Domains (3) summary
      pfam00641
      Location:250 → 279
      zf-RanBP; Zn-finger in Ran binding protein and others
      cd16784
      Location:382 → 440
      mRING-HC-C2H2C4_MDM4; Modified RING finger, HC subclass (C2H2C4-type), found in protein MDM4 and similar proteins
      cd17673
      Location:29 → 107
      MDM4; p53-binding domain found in MDM4 and similar proteins

    4. XM_028852261.1 → XP_028708094.1  protein Mdm4 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RJC8, A0A5S6R9E2, A0A8J8XCI6, G7MEU6, H9EV85, I0FL33
      Conserved Domains (3) summary
      pfam00641
      Location:300 → 329
      zf-RanBP; Zn-finger in Ran binding protein and others
      cd16784
      Location:432 → 490
      mRING-HC-C2H2C4_MDM4; Modified RING finger, HC subclass (C2H2C4-type), found in protein MDM4 and similar proteins
      cd17673
      Location:29 → 107
      MDM4; p53-binding domain found in MDM4 and similar proteins

    RNA

    1. XR_003732171.1 RNA Sequence

    2. XR_003732172.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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