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    NOS2 nitric oxide synthase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 706921, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NOS2provided by VGNC
    Official Full Name
    nitric oxide synthase 2provided by VGNC
    Primary source
    VGNC:VGNC:75369
    See related
    Ensembl:ENSMMUG00000010083
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    INOS; NOS2A
    Orthologs
    human mouse all
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    Genomic context

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    See NOS2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (23369455..23411384, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (21737350..21779304, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 N-like Neighboring gene galectin-9-like Neighboring gene LYR motif containing 9 Neighboring gene small Cajal body-specific RNA 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of inflammatory cytokines and inducible nitric oxide synthase in brains of SIV-infected rhesus monkeys: applications to HIV-induced central nervous system disease. Lane TE, et al. Mol Med, 1996 Jan. PMID 8900532, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nitric oxide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nitric oxide synthase, inducible
    Names
    NOS type II
    inducible NO synthase
    inducible NOS
    inducible nitric oxide synthase
    nitric oxide synthase 2, inducible
    nitric oxide synthase 2A
    peptidyl-cysteine S-nitrosylase NOS2
    XP_014974372.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      23369455..23411384 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015118886.2 → XP_014974372.2  nitric oxide synthase, inducible

      UniProtKB/TrEMBL
      A0A5F8AQS9
      Related
      ENSMMUP00000080305.1, ENSMMUT00000079307.1
      Conserved Domains (3) summary
      cd00795
      Location:84 → 496
      NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
      pfam00258
      Location:541 → 672
      Flavodoxin_1
      cl06868
      Location:736 → 1132
      FNR_like; Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46660.1 GenPept UniProtKB/Swiss-Prot:O46660

    Gene LinkOut

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