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    FADS2 fatty acid desaturase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719037, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FADS2provided by VGNC
    Official Full Name
    fatty acid desaturase 2provided by VGNC
    Primary source
    VGNC:VGNC:72472
    Locus tag
    EGK_06129
    See related
    Ensembl:ENSMMUG00000000327
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FADS2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (12250536..12295023, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (12370117..12411006, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene RAB3A interacting protein like 1 Neighboring gene fatty acid desaturase 3 Neighboring gene prostaglandin E synthase 3 pseudogene Neighboring gene fatty acid-binding protein 5 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acyl-CoA 6-desaturase
    NP_001181646.1
    XP_028688696.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194717.3 → NP_001181646.1  acyl-CoA 6-desaturase

      See identical proteins and their annotated locations for NP_001181646.1

      Status: VALIDATED

      Source sequence(s)
      QNVO02000104
      UniProtKB/TrEMBL
      A0A1D5QW98, A0A8J8Y2M6, F6YUF6, G7NCV5
      Related
      ENSMMUP00000000439.2, ENSMMUT00000000475.4
      Conserved Domains (2) summary
      cd03506
      Location:162 → 412
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
      pfam00173
      Location:22 → 95
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      12250536..12295023 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028832863.1 → XP_028688696.1  acyl-CoA 6-desaturase isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q079, A0A1D5QW98
      Related
      ENSMMUP00000041441.2, ENSMMUT00000065095.2
      Conserved Domains (2) summary
      cd03506
      Location:162 → 412
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
      pfam00173
      Location:22 → 95
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version

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