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    HDAC6 histone deacetylase 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711363, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HDAC6provided by VGNC
    Official Full Name
    histone deacetylase 6provided by VGNC
    Primary source
    VGNC:VGNC:73164
    See related
    Ensembl:ENSMMUG00000016465
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HDAC6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (48802330..48825970)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (49044106..49068065)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene glyoxalase domain containing 5 Neighboring gene GATA binding protein 1 Neighboring gene uncharacterized LOC114675082 Neighboring gene ES cell expressed Ras Neighboring gene proprotein convertase subtilisin/kexin type 1 inhibitor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone deacetylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of histone deacetylase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone deacetylase 6
    NP_001181125.1
    XP_014982803.1
    XP_014982805.1
    XP_014982806.1
    XP_014982808.1
    XP_014982809.1
    XP_014982810.1
    XP_028697651.1
    XP_028697652.1
    XP_028697653.1
    XP_028697654.1
    XP_028697655.1
    XP_028697656.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194196.2 → NP_001181125.1  histone deacetylase 6

      See identical proteins and their annotated locations for NP_001181125.1

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02003165
      UniProtKB/TrEMBL
      A0A5F7ZFQ0, F7GBE5, H9ER82
      Related
      ENSMMUP00000069740.1, ENSMMUT00000099875.1
      Conserved Domains (4) summary
      cd10003
      Location:485 → 835
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:838 → 1071
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1133 → 1195
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      48802330..48825970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127317.2 → XP_014982803.1  histone deacetylase 6 isoform X3

      UniProtKB/TrEMBL
      F7GBF5
      Related
      ENSMMUP00000021637.4, ENSMMUT00000023129.4
      Conserved Domains (3) summary
      cd10003
      Location:531 → 881
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:141 → 477
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1179 → 1241
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    2. XM_015127322.2 → XP_014982808.1  histone deacetylase 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
      Conserved Domains (3) summary
      cd10003
      Location:489 → 839
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1137 → 1199
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    3. XM_028841818.1 → XP_028697651.1  histone deacetylase 6 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, F7GBE5, H9ER82
      Related
      ENSMMUP00000078635.1, ENSMMUT00000084898.1
      Conserved Domains (4) summary
      cd10003
      Location:485 → 835
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:838 → 1071
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1133 → 1195
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    4. XM_028841823.1 → XP_028697656.1  histone deacetylase 6 isoform X6

      UniProtKB/TrEMBL
      A0A5F7Z9U3, A0A5F7ZHA3
      Related
      ENSMMUP00000061394.1, ENSMMUT00000085908.1
      Conserved Domains (4) summary
      cd10003
      Location:434 → 784
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:44 → 380
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:787 → 1020
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1082 → 1144
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    5. XM_015127319.2 → XP_014982805.1  histone deacetylase 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
      Conserved Domains (3) summary
      cd10003
      Location:489 → 839
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1137 → 1199
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    6. XM_028841822.1 → XP_028697655.1  histone deacetylase 6 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, F7GBE5, H9ER82
      Conserved Domains (4) summary
      cd10003
      Location:485 → 835
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:838 → 1071
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1133 → 1195
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    7. XM_028841821.1 → XP_028697654.1  histone deacetylase 6 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, F7GBE5, H9ER82
      Related
      ENSMMUP00000063454.1, ENSMMUT00000079887.1
      Conserved Domains (4) summary
      cd10003
      Location:485 → 835
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:838 → 1071
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1133 → 1195
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    8. XM_028841819.1 → XP_028697652.1  histone deacetylase 6 isoform X4

      UniProtKB/TrEMBL
      A0A5F7ZFQ0
      Conserved Domains (4) summary
      cd10003
      Location:503 → 853
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:113 → 449
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:856 → 1089
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1151 → 1213
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    9. XM_028841820.1 → XP_028697653.1  histone deacetylase 6 isoform X5

      UniProtKB/TrEMBL
      A0A5F7ZFQ0
      Conserved Domains (4) summary
      cd10003
      Location:499 → 849
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:113 → 449
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam05109
      Location:852 → 1085
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam02148
      Location:1147 → 1209
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    10. XM_015127323.2 → XP_014982809.1  histone deacetylase 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
      Related
      ENSMMUP00000063991.1, ENSMMUT00000084196.1
      Conserved Domains (3) summary
      cd10003
      Location:489 → 839
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1137 → 1199
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    11. XM_015127320.2 → XP_014982806.1  histone deacetylase 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
      Conserved Domains (3) summary
      cd10003
      Location:489 → 839
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1137 → 1199
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

    12. XM_015127324.2 → XP_014982810.1  histone deacetylase 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
      Related
      ENSMMUP00000021638.4, ENSMMUT00000023130.4
      Conserved Domains (3) summary
      cd10003
      Location:489 → 839
      HDAC6-dom2; Histone deacetylase 6, domain 2
      cd11682
      Location:99 → 435
      HDAC6-dom1; Histone deacetylase 6, domain 1
      pfam02148
      Location:1137 → 1199
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    Nucleotide Protein
    Heading Accession and Version

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