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    NOX1 NADPH oxidase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701376, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NOX1provided by VGNC
    Official Full Name
    NADPH oxidase 1provided by VGNC
    Primary source
    VGNC:VGNC:75374
    Locus tag
    EGK_20729
    See related
    Ensembl:ENSMMUG00000004178
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NOX1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (97649673..97671765, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (95030268..95052402, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene double-strand-break repair protein rad21 homolog pseudogene Neighboring gene small nucleolar RNA SNORA9 Neighboring gene cleavage stimulation factor subunit 2 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene ribosome biogenesis protein NSA2 homolog pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables superoxide-generating NAD(P)H oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH oxidase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      97649673..97671765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028842040.1 → XP_028697873.1  NADPH oxidase 1

      UniProtKB/TrEMBL
      A0A8J8YRD2, F6X2U4, G7NSF9
      Related
      ENSMMUP00000005594.3, ENSMMUT00000005939.4
      Conserved Domains (2) summary
      cd06186
      Location:312 → 579
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      pfam01794
      Location:81 → 228
      Ferric_reduct; Ferric reductase like transmembrane component
    Nucleotide Protein
    Heading Accession and Version

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