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    HGS hepatocyte growth factor-regulated tyrosine kinase substrate [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714385, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HGSprovided by VGNC
    Official Full Name
    hepatocyte growth factor-regulated tyrosine kinase substrateprovided by VGNC
    Primary source
    VGNC:VGNC:73375
    See related
    Ensembl:ENSMMUG00000008833
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See HGS in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (78031179..78050780)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (75550923..75572738)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 6G Neighboring gene coiled-coil domain containing 137 Neighboring gene oxidoreductase like domain containing 1 Neighboring gene ADP ribosylation factor like GTPase 16 Neighboring gene mitochondrial ribosomal protein L12 Neighboring gene solute carrier family 25 member 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hepatocyte growth factor-regulated tyrosine kinase substrate

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261611.2 → NP_001248540.1  hepatocyte growth factor-regulated tyrosine kinase substrate

      See identical proteins and their annotated locations for NP_001248540.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048661
      UniProtKB/TrEMBL
      G7NHA0, H9ZF73
      Related
      ENSMMUP00000011578.3, ENSMMUT00000012345.4
      Conserved Domains (4) summary
      cd03569
      Location:4 → 145
      VHS_Hrs_Vps27p; VHS domain family, Hrs and Vps27p subfamily; composed of Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and its yeast homolog Vps27p (vacuolar protein sorting). The VHS domain, an essential part of Hrs/Vps27p, has a superhelical ...
      cd15720
      Location:159 → 219
      FYVE_Hrs; FYVE domain found in hepatocyte growth factor (HGF)-regulated tyrosine kinase substrate (Hrs) and similar proteins
      pfam12210
      Location:407 → 501
      Hrs_helical; Hepatocyte growth factor-regulated tyrosine kinase substrate
      cl24005
      Location:509 → 560
      DUF2570; Protein of unknown function (DUF2570)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      78031179..78050780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835658.1 → XP_028691491.1  hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1

      UniProtKB/TrEMBL
      G7NHA0
      Conserved Domains (5) summary
      PRK06302
      Location:538 → 619
      PRK06302; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated
      cd15720
      Location:159 → 219
      FYVE_Hrs; FYVE domain found in hepatocyte growth factor (HGF)-regulated tyrosine kinase substrate (Hrs) and similar proteins
      pfam05672
      Location:492 → 562
      MAP7; MAP7 (E-MAP-115) family
      pfam12210
      Location:407 → 501
      Hrs_helical; Hepatocyte growth factor-regulated tyrosine kinase substrate
      cd03569
      Location:6 → 143
      VHS_Hrs; VHS (Vps27/Hrs/STAM) domain of Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs
    Nucleotide Protein
    Heading Accession and Version

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