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    KLHL22 kelch like family member 22 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694160, updated on 5-Mar-2024

    Summary

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    Gene symbol
    KLHL22
    Gene description
    kelch like family member 22
    Locus tag
    EGK_02809
    See related
    Ensembl:ENSMMUG00000017171
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KLHL22 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (32112708..32166898)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (62254976..62308509, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 15 Neighboring gene mitochondrial carrier homolog 2 pseudogene Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene kelch-like protein 12 pseudogene Neighboring gene scavenger receptor class F member 2 Neighboring gene uncharacterized LOC114670593 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein monoubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitotic spindle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in polar microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch-like protein 22
    Names
    kelch-like 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261588.1 → NP_001248517.1  kelch-like protein 22

      See identical proteins and their annotated locations for NP_001248517.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048480
      UniProtKB/TrEMBL
      A0A5F7ZUS1, A0A8J8YHH4, G7N3A6, H9G0X4
      Related
      ENSMMUP00000076229.1, ENSMMUT00000081076.1
      Conserved Domains (4) summary
      PHA03098
      Location:52 → 592
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:340 → 385
      Kelch; KELCH repeat [structural motif]
      cd18461
      Location:147 → 250
      BACK_KLHL22; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 22 (KLHL22)
      cl38908
      Location:27 → 151
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      32112708..32166898
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827145.1 → XP_028682978.1  kelch-like protein 22 isoform X1

      UniProtKB/TrEMBL
      F7HGC9
      Conserved Domains (4) summary
      PHA03098
      Location:52 → 503
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:340 → 385
      Kelch; KELCH repeat [structural motif]
      cd18461
      Location:147 → 250
      BACK_KLHL22; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 22 (KLHL22)
      cl38908
      Location:27 → 151
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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