SPOPL speckle type BTB/POZ protein like [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SPOPLprovided by VGNC
Official Full Name: speckle type BTB/POZ protein likeprovided by VGNC
Primary source: VGNC:VGNC:78007
Locus tag: EGK_04395
See related: Ensembl:ENSMMUG00000002560
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	12	NC_041765.1 (25579528..25644728)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	12	NC_027904.1 (24638899..24704309)

Chromosome 12 - NC_041765.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D2S1795 (e-PCR)
- UniSTS:19723

SHGC-36231 (e-PCR)
- UniSTS:24367

WI-11856 (e-PCR)
- UniSTS:21093

RH104408 (e-PCR)
- UniSTS:98733

D2S2867 (e-PCR)
- UniSTS:28923

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin protein ligase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: speckle-type POZ protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001266382.1 → NP_001253311.1 speckle-type POZ protein-like

See identical proteins and their annotated locations for NP_001253311.1

Status: PROVISIONAL

Source sequence(s)

JU475422

UniProtKB/TrEMBL

A0A8J8Y024, F7HSR0, G7N807

Related

ENSMMUP00000003441.2, ENSMMUT00000003641.4

Conserved Domains (4) summary

smart00225
Location:201 → 297

BTB; Broad-Complex, Tramtrack and Bric a brac

cd14734
Location:297 → 377

SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins

pfam00651
Location:190 → 294

BTB; BTB/POZ domain

cl02446
Location:28 → 166

MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041765.1 Reference Mmul_10 Primary Assembly

Range

25579528..25644728

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015110019.2 → XP_014965505.2 speckle-type POZ protein-like isoform X1

Conserved Domains (2) summary

cd18343
Location:104 → 226

BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)

cd18519
Location:222 → 317

BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)
XM_015110018.2 → XP_014965504.2 speckle-type POZ protein-like isoform X1

Conserved Domains (2) summary

cd18343
Location:104 → 226

BTB_POZ_SPOPL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in speckle-type POZ protein-like (SPOPL)

cd18519
Location:222 → 317

BACK_SPOPL; BACK (BTB and C-terminal Kelch) domain found in speckle-type POZ protein-like (SPOPL)
XM_015110020.2 → XP_014965506.1 speckle-type POZ protein-like isoform X2

Conserved Domains (4) summary

smart00225
Location:85 → 181

BTB; Broad-Complex, Tramtrack and Bric a brac

cd14734
Location:181 → 261

SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins

pfam00651
Location:74 → 178

BTB; BTB/POZ domain

cl02446
Location:1 → 50

MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...