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    PRKG1 protein kinase cGMP-dependent 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703356, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRKG1provided by VGNC
    Official Full Name
    protein kinase cGMP-dependent 1provided by VGNC
    Primary source
    VGNC:VGNC:76419
    See related
    Ensembl:ENSMMUG00000010844
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PRKG1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (85653599..86993604, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (80514955..81911998, complement)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114669992 Neighboring gene uncharacterized LOC114669993 Neighboring gene ADP-ribosylation factor-like protein 4A Neighboring gene cleavage stimulation factor subunit 2 tau variant Neighboring gene ras suppressor protein 1 pseudogene Neighboring gene microRNA mir-605 Neighboring gene coiled-coil domain-containing protein 58 pseudogene Neighboring gene APOBEC1 complementation factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cGMP-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cGMP-dependent protein kinase 1
    Names
    protein kinase, cGMP-dependent, type I
    XP_001099261.1
    XP_001099460.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      85653599..86993604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001099261.4 → XP_001099261.1  cGMP-dependent protein kinase 1 isoform X2

      See identical proteins and their annotated locations for XP_001099261.1

      UniProtKB/TrEMBL
      F7G3M3
      Conserved Domains (4) summary
      cd12085
      Location:2 → 49
      DD_cGKI-alpha; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I alpha
      smart00133
      Location:621 → 664
      S_TK_X; Extension to Ser/Thr-type protein kinases
      cd00038
      Location:222 → 326
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd05572
      Location:366 → 626
      STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)

    2. XM_001099460.4 → XP_001099460.1  cGMP-dependent protein kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_001099460.1

      UniProtKB/TrEMBL
      F7G3L7
      Related
      ENSMMUP00000014212.3, ENSMMUT00000015166.4
      Conserved Domains (4) summary
      cd12086
      Location:4 → 55
      DD_cGKI-beta; Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I beta
      smart00133
      Location:636 → 679
      S_TK_X; Extension to Ser/Thr-type protein kinases
      cd00038
      Location:237 → 341
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd05572
      Location:381 → 641
      STKc_cGK; Catalytic domain of the Serine/Threonine Kinase, cGMP-dependent protein kinase (cGK or PKG)
    Nucleotide Protein
    Heading Accession and Version

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