U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DUSP8 dual specificity phosphatase 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720960, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DUSP8provided by VGNC
    Official Full Name
    dual specificity phosphatase 8provided by VGNC
    Primary source
    VGNC:VGNC:100918
    See related
    Ensembl:ENSMMUG00000023132
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DUSP8 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (1618392..1636874, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (1387798..1402882, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene BR serine/threonine kinase 2 Neighboring gene uncharacterized LOC114672202 Neighboring gene MOB kinase activator 2 Neighboring gene uncharacterized LOC106993156 Neighboring gene uncharacterized LOC100429866 Neighboring gene keratin-associated protein 5-4-like Neighboring gene uncharacterized LOC106993157

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dual specificity protein phosphatase 8

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      1618392..1636874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028833015.1 → XP_028688848.1  dual specificity protein phosphatase 8 isoform X3

      Conserved Domains (2) summary
      cd01446
      Location:10 → 137
      DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
      cd14645
      Location:150 → 300
      DSP_DUSP8; dual specificity phosphatase domain of dual specificity protein phosphatase 8

    2. XM_028833014.1 → XP_028688847.1  dual specificity protein phosphatase 8 isoform X2

      Conserved Domains (2) summary
      cd01446
      Location:80 → 193
      DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
      cd14645
      Location:206 → 356
      DSP_DUSP8; dual specificity phosphatase domain of dual specificity protein phosphatase 8

    3. XM_015113327.2 → XP_014968813.2  dual specificity protein phosphatase 8 isoform X1

      UniProtKB/TrEMBL
      F7DFT5
      Related
      ENSMMUP00000030450.4, ENSMMUT00000032541.4
      Conserved Domains (2) summary
      cd01446
      Location:80 → 207
      DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
      cd14645
      Location:220 → 370
      DSP_DUSP8; dual specificity phosphatase domain of dual specificity protein phosphatase 8
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.