NRP1 neuropilin 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: NRP1provided by VGNC
Official Full Name: neuropilin 1provided by VGNC
Primary source: VGNC:VGNC:75532
Locus tag: EGK_19578
See related: Ensembl:ENSMMUG00000017588
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	9	NC_041762.1 (34118596..34277530, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	9	NC_027901.1 (33405511..33563286, complement)

Chromosome 9 - NC_041762.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH70034 (e-PCR)
- UniSTS:22785

RH65747 (e-PCR)
- UniSTS:8233

G20549 (e-PCR)
- UniSTS:74679

A005W14 (e-PCR)
- UniSTS:74680

RH120752 (e-PCR)
- UniSTS:132831

D10S1654 (e-PCR), detects polymorphism
- UniSTS:58084

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables semaphorin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables vascular endothelial growth factor receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in angiogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in axon guidance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in vascular endothelial growth factor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: neuropilin-1

Names: Vascular endothelial cell growth factor 165 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265816.1 → NP_001252745.1 neuropilin-1 precursor

See identical proteins and their annotated locations for NP_001252745.1

Status: PROVISIONAL

Source sequence(s)

JV635572

UniProtKB/TrEMBL

A0A8J8YRP3, F7HHM6, F7HHN8, G7N1U4

Related

ENSMMUP00000036036.1, ENSMMUT00000043022.3

Conserved Domains (4) summary

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

pfam11980
Location:845 → 923

DUF3481; C-terminal domain of neuropilin glycoprotein

pfam00629
Location:650 → 810

MAM; MAM domain, meprin/A5/mu

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041762.1 Reference Mmul_10 Primary Assembly

Range

34118596..34277530 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015146734.2 → XP_015002220.1 neuropilin-1 isoform X4

UniProtKB/TrEMBL

F7HHN6

Related

ENSMMUP00000036031.3, ENSMMUT00000043017.3

Conserved Domains (6) summary

cd06263
Location:615 → 768

MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...

pfam11980
Location:808 → 885

DUF3481; Domain of unknown function (DUF3481)

smart00137
Location:610 → 769

MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)

smart00231
Location:274 → 424

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
XM_015146732.2 → XP_015002218.1 neuropilin-1 isoform X2

Conserved Domains (6) summary

cd06263
Location:643 → 796

MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...

pfam11980
Location:836 → 913

DUF3481; Domain of unknown function (DUF3481)

smart00137
Location:638 → 797

MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)

smart00231
Location:274 → 424

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
XM_015146733.2 → XP_015002219.1 neuropilin-1 isoform X3

UniProtKB/TrEMBL

F6WJ42

Related

ENSMMUP00000023153.4, ENSMMUT00000024738.4

Conserved Domains (6) summary

cd06263
Location:650 → 803

MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...

pfam11980
Location:826 → 903

DUF3481; Domain of unknown function (DUF3481)

smart00137
Location:645 → 804

MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)

smart00231
Location:274 → 424

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
XM_028853313.1 → XP_028709146.1 neuropilin-1 isoform X1

UniProtKB/TrEMBL

A0A8J8YRP3, F7HHM6, F7HHN8, G7N1U4

Related

ENSMMUP00000036030.3, ENSMMUT00000043016.3

Conserved Domains (4) summary

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

pfam11980
Location:845 → 923

DUF3481; C-terminal domain of neuropilin glycoprotein

pfam00629
Location:650 → 810

MAM; MAM domain, meprin/A5/mu
XM_028853312.1 → XP_028709145.1 neuropilin-1 isoform X1

UniProtKB/TrEMBL

A0A8J8YRP3, F7HHM6, F7HHN8, G7N1U4

Conserved Domains (4) summary

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.

pfam11980
Location:845 → 923

DUF3481; C-terminal domain of neuropilin glycoprotein

pfam00629
Location:650 → 810

MAM; MAM domain, meprin/A5/mu
XM_015146735.2 → XP_015002221.1 neuropilin-1 isoform X5

Conserved Domains (3) summary

smart00231
Location:274 → 424

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain

cd00041
Location:27 → 140

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00057
Location:277 → 423

FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.